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Organic compounds that consists entirely of hydrogen and carbon elements usually organized in a chain; some may have a cyclic structure. Includes hydrocarbons that have additional functional groups such as aromatic rings.
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Tau protein (592-597), human TFA, is a peptide fragment of human Tau protein. The dysfunction of Tau protein is involved in neurodegeneration and dementia, making this compound relevant for neurodegenerative disease research.
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DI-591 is a potent, high-affinity, and cell-permeable inhibitor of the DCN1-UBC12 interaction. It selectively inhibits the neddylation of cullin 3, with minimal or no effect on other cullin family members.
Binds to DCN1 and DCN2 with Ki values of 12 nM and 10.4 nM, respectively
Shows no significant binding to DCN3, DCN4, and DCN5 proteins
Serves as an excellent probe compound for investigating the role of cullin 3 CRL
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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ADH-503 (CAS 2055362-74-6) also known as (Z)-Leukadherin-1 choline is an orally bioavailable small molecule that functions as an allosteric agonist This compound modulates macrophage phenotypes by promoting repolarization of tumor-associated macrophages resulting in a reduction of immunosuppressive myeloid cell infiltration within the tumor microenvironment Additionally ADH-503 has been shown to enhance dendritic cell responses These properties make ADH-503 a valuable tool for investigating macrophage regulation and immune modulation in the context of cancer research
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Bpin-Cyclohexene-COOEt is a PROTAC linker from the PEG class, primarily used in the synthesis of PROTAC molecules. This chemical appears as a colorless to light yellow liquid, suitable for laboratory research and the manufacture of substances. It is important to note that this product is intended for research purposes only and has not been validated for medical applications.
PROTAC linker for synthesizing PROTAC molecules
Clear to light yellow liquid appearance
Purity greater than or equal to 97.0%
Molecular weight of 280.17
Store pure form at -20°C for up to 3 years
Unstable in solutions; use freshly prepared solutions
Stable under recommended storage conditions
Intended for research use only
Not validated for medical applications
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A monounsaturated fatty acid and isomer of oleic acid; major component of plant lipids; rats fed a diet containing it have a reduction in arachidonic acid levels and an increase in linoleic acid levels in the heart, liver, and blood; has been used in a composite membrane to study plant uptake; has been used in the synthesis of new biosurfactants (sophorolipids)
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Butyne-DOTA-tris(t-butyl ester) is a DOTA-based bifunctional chelator designed for conjugation of peptides and radionuclides. It is intended for radiopharmaceutical development and tumor pre-targeting workflows, supplied as a white to off-white solid.
Bifunctional DOTA derivative for peptide and radionuclide conjugation.
Supports tumor pre-targeting and radiopharmaceutical research.
High purity suitable for analytical and synthetic applications (98.5%).
Molecular weight 623.82 g/mol; formula C32H57N5O7.
Available in small research pack sizes, including 25 MG.
Provided with SDS and documentation for safe handling.
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VE-821(ATR inhibitor IV) is a potent and selective ATP competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM in cell-free assays shows inhibition of H2AX phosphorylation minimal activity against PIKKs ATM DNA-PK mTOR and PI3K
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