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Organic compounds that consists entirely of hydrogen and carbon elements usually organized in a chain; some may have a cyclic structure. Includes hydrocarbons that have additional functional groups such as aromatic rings.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
β-Carotene (standard) is an analytical reference standard of the provitamin A carotenoid supplied for research and analytical use. Provided as a 10 mg solid, it is commonly used for calibration, method development, and quantitative analysis; a certificate of analysis and safety data sheet are available.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
VE-821 (CAS 1232410-49-9) is a selective ATP-competitive inhibitor of ATR (ataxia telangiectasia and Rad3-related) kinase a critical regulator involved in DNA damage response signaling VE-821 exhibits potent ATR inhibition with a Ki value of 13 nM and minimal off-target activity toward other PI3K-related kinases such as ATM DNA-PK mTOR and PI3K In cellular models VE-821 effectively reduces phosphorylation of ATR substrates including Chk1 at Ser345 thereby sensitizing HL-60 leukemia and pancreatic cancer cell lines (e g PSN-1 MiaPaCa-2) to chemotherapy (gemcitabine) and radiation-induced cytotoxicity VE-821 is utilized as a research tool in the study of DNA damage responses and cancer vulnerabilities
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More