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Organic compounds that consists entirely of hydrogen and carbon elements usually organized in a chain; some may have a cyclic structure. Includes hydrocarbons that have additional functional groups such as aromatic rings.
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A long-chain saturated fatty acid; a major component of cocoa butter and has also been found in beef fat and vegetable oils; does not induce hypercholesterolemia or raise LDL-cholesterol unlike many long-chain saturated fatty acids
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Stearic acid-PEG-Mal (average MW 5000) is a heterobifunctional pegylated lipid consisting of a stearic acid moiety linked to a polyethylene glycol chain terminated with a maleimide group. It is used as a thiol-reactive amphiphilic reagent for conjugation to cysteine-containing biomolecules, surface modification, and nanoparticle functionalization in biochemical assays. For research use only.
Heterobifunctional reagent with maleimide for thiol conjugation.
Average molecular weight 5000 providing a PEG spacer.
Amphiphilic stearic acid tail enables membrane or particle incorporation.
Suitable for surface modification and nanoparticle functionalization.
Storage: sealed at 4°C; in solvent store at -80°C up to 6 months or -20°C up to 1 month.
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Dimethyl pentadecanedioate is the dimethyl ester of pentadecanedioic acid and is supplied for laboratory research use as a chemical reagent and analytical standard. It is suitable for use in organic synthesis, method development, and other analytical applications requiring a high-purity long-chain diester.
Purity approximately 99%.
Molecular weight 300.43 g/mol.
Molecular formula C17H32O4.
CAS number 36575-82-3.
Pack size 50 G.
Suitable for organic synthesis and analytical method development.
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Octadecane is an alkane used to store thermal energy at ambient temperature as a phase change material. It is for research use only and not sold to patients.
Purity of 98.0%
Molecular weight: 254.49
Formula: C18H38
Appearance: solid below 28°C, liquid above 28°C
Color: colorless to off-white
Melting/freezing point: 28°C
Target: biochemical assay reagents
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MD-224 is a PROTAC small-molecule degrader of murine double minute 2 (MDM2) used in research to induce targeted protein degradation and study p53 pathway modulation. It is supplied as a high-purity solid with supporting analytical and safety documentation.
High purity suitable for cellular and in vivo research.
Contains an alkyne group for click chemistry conjugation.
Characterized by LC-MS and supplied with a certificate of analysis and SDS.
Available in multiple pack sizes and solution formats for flexible use.
Potent activity at sub-nanomolar concentrations for MDM2 degradation.
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224-Trimethylpentane (TMP Isooctane) is a saturated branched hydrocarbon. It has been reported to be nephrotoxic to male rats. Density and viscosity of TMP at various temperatures (198K - 348K) and pressures (100MPa) has been evaluated. It has been indentified as nephrotoxicity inducing component in unleaded gasoline.
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An esterified form of 12-oxo stearic acid; has been found in esterified L. chinensis and L. decipiens pulp oils and serves as a measure of 12-oxo stearic acid content
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Dynole 2-24 is an indole-based dynamin GTPase inhibitor used as a research reagent to inhibit dynamin I and II and to block clathrin-mediated endocytosis in cells.
Potent inhibitor of dynamin I (IC50 = 0.56 μM).
Active in cells to inhibit clathrin-mediated endocytosis (IC50 ≈ 1.9 μM).
Shows selectivity for dynamin I over dynamin II (≈4.4-fold).
High purity suitable for biochemical and cellular assays.
Available in small research quantities as an oil for convenient handling.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. MD-224 is a highly potent and efficacious MDM2 degrader based on the proteolysistargeting chimera (PROTAC) conceptand as a new class of anticancer agent. purity: 100%
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