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Organic compounds that consists entirely of hydrogen and carbon elements usually organized in a chain; some may have a cyclic structure. Includes hydrocarbons that have additional functional groups such as aromatic rings.
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Hexadecane-1-thiol-d33 is the deuterium labeled Hexadecane-1-thiol. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, primarily as tracers for quantitation during the drug development process.
This compound can be used as a tracer.
This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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DI-591 is a potent, high-affinity, and cell-permeable inhibitor of the DCN1-UBC12 interaction. It selectively inhibits the neddylation of cullin 3, with minimal or no effect on other cullin family members.
Binds to DCN1 and DCN2 with Ki values of 12 nM and 10.4 nM, respectively
Shows no significant binding to DCN3, DCN4, and DCN5 proteins
Serves as an excellent probe compound for investigating the role of cullin 3 CRL
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