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MD-224 is a small-molecule proteolysis-targeting chimera (PROTAC) that induces degradation of the E3 ubiquitin ligase MDM2 and is used in biochemical and cell-based studies of the MDM2-p53 pathway.
Induces rapid MDM2 degradation at sub-nanomolar concentrations.
High purity suitable for research applications.
Molecular weight 889.80 g/mol; formula C48H43Cl2FN6O6.
Supplied as a 50 mg solid for laboratory use.
Intended for research use only; not for human or clinical use.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More