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Organic compounds that consists entirely of hydrogen and carbon elements usually organized in a chain; some may have a cyclic structure. Includes hydrocarbons that have additional functional groups such as aromatic rings.
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Stearic acid is a long-chain dietary saturated fatty acid that significantly reduces visceral fat by inducing apoptosis of preadipocytes. It is utilized in the study of cardiovascular and metabolic diseases.
Target: Endogenous metabolite, Apoptosis
Research areas: Cancer, Cardiovascular disease, Metabolic disease
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An esterified form of 12-oxo stearic acid; has been found in esterified L. chinensis and L. decipiens pulp oils and serves as a measure of 12-oxo stearic acid content
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2-Methylcyclopentane-1,3-dione is a chemical compound that serves as a key intermediate in the total synthesis of steroids. It is also utilized as a drug intermediate, and for general laboratory chemical applications including the manufacture of various substances.
Key intermediate for total synthesis of steroids
Drug intermediate
Suitable for laboratory chemical applications
Used in the manufacture of substances
White to light yellow solid appearance
High purity of 99.96% (HPLC)
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MD-224 is a first-in-class and highly potent small-molecule human murine double minute 2 (MDM2) degrader based on the proteolysistargeting chimera (PROTAC) concept MD-224 consists of ligands for Cereblon and MDM2 MD-224 induces rapid degradation of MDM2 at concentrations 1 nM in human leukemia cells and achieves an IC50 value of 1 5 nM in inhibition of growth of RS4 11 cells MD-224 has the potential to be a new class of anticancer agent[1] MD-224 is a click chemistry reagent it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
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Artemether (SM-224 CAS 71963-77-4) is a small-molecule inhibitor designed to inhibit the proliferation of Plasmodium species and impair the viability of Schistosoma japonicum Artemether exerts its biological activity primarily through metabolism in parasites generating reactive oxygen species that damage parasite biomolecules In in vitro studies Artemether demonstrates inhibitory activity against Schistosoma mansoni with IC50 values ranging approximately from 30 50 nM Based on these pharmacological properties Artemether holds research potential in antimalarial drug development and the study of parasite infection mechanisms
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A bioactive fatty acid; accumulates in PMA-stimulated primary human monocytes and neutrophils as well as murine neutrophils; induces DNA release from primary human neutrophils
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A hydroxy fatty acid; has been found in humans and U. armoricana; reduces growth of EAT cells (100 μM); elevated in human joint synovial fluid after ankle fracture and in patients with Buruli ulcer disease
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Stearic anhydride is an organic anhydride used as a biochemical reagent in life-science research. Supplied as a white to off-white solid, it is used as a synthetic intermediate and reagent in biochemical assays and organic synthesis. Intended for research use only; not for human or clinical use.
White to off-white solid appearance.
High purity (99.24%).
Molecular formula C36H70O3; molecular weight 550.94 g·mol-1.
CAS number 638-08-4.
Available in small laboratory pack sizes (5 g, 10 g, 50 g).
Store at room temperature; in solution: -80 °C (2 years), -20 °C (1 year).
For research use only; not for sale to patients.
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