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Topotecan hydrochloride is a potent Topoisomerase I inhibitor with significant antineoplastic activities. It is intended for research and analytical applications, playing a role in studies related to cancer, autophagy, and apoptosis.
Potent Topoisomerase I inhibitor
Demonstrates antineoplastic activities
Inhibits the proliferation of human glioma cells
Induces cell cycle arrest in G0/G1 and S phases
Promotes apoptosis in various cell lines
Store at 4°C, sealed, away from moisture and light
Store in solvent at -80°C for 2 years or -20°C for 1 year
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7α-Hydroxycholesterol is a cholesterol oxide that can serve as a biomarker for oxidative stress and lipid peroxidation. It exhibits cytotoxic and pro-inflammatory activities. This compound can also inhibit sterol synthesis and reduce the activity of HMG-CoA reductase. It is used in the research of diseases such as diabetes and atherosclerosis.
Functions as a biomarker for oxidative stress and lipid peroxidation.
Possesses cytotoxic and pro-inflammatory activities.
Inhibits sterol synthesis.
Reduces the activity of HMG-CoA reductase.
Applicable in the research of diseases like diabetes and atherosclerosis.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Tivanisiran (SYL1001) is a double-stranded small interfering RNA (siRNA) designed to silence transient receptor potential vanilloid 1 (TRPV1) mRNA for research into dry eye disease. It is supplied as an oligonucleotide reagent intended for laboratory and preclinical gene-silencing studies.
Silences TRPV1 mRNA to reduce ocular discomfort in dry eye models.
Double-stranded siRNA sequence for targeted gene knockdown.
High purity suitable for research applications (97.5%).
Characterized molecular weight approximately 12,068 Da.
Available in small pack sizes suitable for experiments (for example, 5 mg).
Sequence information provided to support assay design and verification.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
CO23 is a selective thyroid hormone receptor alpha (TRα) agonist used in research to study growth, development, and thyroid signaling. It has been reported to cross the blood-brain barrier and is supplied as a high-purity research chemical for in vitro and in vivo studies.
Selective TRα agonist for targeted thyroid receptor modulation.
Demonstrated blood-brain barrier penetration.
High purity (98.0%) for reliable experimental results.
Soluble in DMSO at 250 mg/mL; ultrasonic assistance recommended.
Solid, off-white to light yellow appearance; powder stable at -20 °C.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
β-Ionone is a small organic compound (C13H20O, MW 192.30 g/mol) used in research as an apoptosis inducer with reported anti-cancer activity in gastric adenocarcinoma SGC7901 cells. It is supplied as solid and solution formats for in vitro and in vivo studies and includes solubility and storage recommendations for reliable handling.
High purity (≈99.85%).
Available as solid and DMSO solution formats for experimental use.
Soluble in DMSO and ethanol; insoluble in water.
Storage recommendations for pure form and for solutions to preserve stability.
Acts as an apoptosis inducer in cell studies.
Molecular formula C13H20O; molecular weight 192.30 g/mol.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Indole-3-pyruvic acid is an endogenous metabolite and keto analogue of tryptophan used as a research reagent and analytical standard in studies of AHR activation, inflammation, and oxidative stress. It is supplied as a high-purity chemical for laboratory use.
High purity suitable for analytical and biochemical applications.
Endogenous metabolite and AHR agonist for pathway studies.
Supplied in research-scale quantities for laboratory testing.
Verified molecular formula and molecular weight for reference.
Useful as a reagent in inflammation and oxidative stress research.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More