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Toronto Research Chemicals | 7-(2-Butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-8-[(3S)-3-piperidinylamino]-1H-purine-2,6-dione | 100mg | 601591821 | B740035 | | 2253964-85-9 | | 472.553 | C25H28N8O2
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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Fedratinib hydrochloride hydrate is the dihydrochloride monohydrate salt of fedratinib, an ATP-competitive, orally active and selective JAK2 inhibitor supplied for research use. The compound is provided as a solid (white to yellow) with high reported purity and is intended for in vitro and preclinical studies; not for human therapeutic use.
High purity (≈99.9%) as reported by supplier.
Molecular weight 615.62 g/mol; formula C27H40Cl2N6O4S.
Packaged in small-scale quantities, commonly available as 2 G.
Recommended storage: solid at 4°C; in solution -20°C to -80°C.
Potent JAK2 inhibitor with reported IC50 ≈3 nM, suitable for signaling and oncology research.
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Ethylene dimethanesulfonate (CAS 4672-49-5) is a methanesulfonate compound known to exert its biological effects through a mild alkylation process Studies indicate that it selectively induces apoptosis in Leydig cells thereby modulating specific cell populations within testicular tissue Due to these properties ethylene dimethanesulfonate serves as a valuable tool in biomedical research for investigating mechanisms of germ cell injury reproductive toxicology and the development of testicular injury models It is also utilized in studies exploring cell signaling pathways and apoptotic mechanisms related to reproductive biology
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