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LQZ-7I is a small-molecule survivin-targeting inhibitor used in research to disrupt survivin dimerization, promote survivin degradation, and reduce tumor growth in xenograft models. It is used in cellular assays and in vivo studies to investigate survivin-related apoptosis pathways.
Inhibits survivin dimerization
Promotes survivin degradation and induces apoptosis
Orally active in xenograft tumor models
Suitable for cellular and in vivo research applications
Reported purity approximately 99.8%
Molecular formula C20H14F2N4; molecular weight 348.35 g/mol
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Amsacrine hydrochloride is a topoisomerase II inhibitor supplied as a research-grade analytical standard. It intercalates DNA and stabilizes topoisomerase II-DNA cleavage complexes, making it suitable for biochemical assays and cell biology studies of DNA damage, cell cycle, and autophagy. Available as a solid and as a DMSO solution, the material is characterized for consistent analytical performance.
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Physalin F is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBMC, decreasing the spontaneous proliferation and cytokine production caused by Human T-lymphotropic virus type 1 (HTLV-1) infection.
Potent anti-inflammatory activity
Immunomodulatory activities
Induces apoptosis of PBMC
Decreases spontaneous proliferation and cytokine production caused by HTLV-1 infection
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Tracheloside is an antiestrogenic lignin that promotes keratinocyte proliferation through ERK1/2 stimulation. It is considered a good candidate to promote wound healing.
Antiestrogenic lignin
Promotes keratinocyte proliferation through ERK1/2 stimulation
Good candidate to promote wound healing
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat. purity: 97%
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