Organosulfur Compounds
Medchemexpress LLC NX-2127 | 2416131-46-7 | C39H45N9O5 | 25 MG
NX-2127 is an orally active PROTAC degrader that targets Bruton's Tyrosine Kinase (BTK). It inhibits the proliferation of BTKC481S mutant TMD8 cells more effectively than Ibrutinib. NX-2127 catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3) and stimulates T cell activation.
- Inhibits proliferation of BTK-C481S mutant TMD8 cells
- Catalyzes degradation of Ikaros (IKZF1) and Aiolos (IKZF3)
- Stimulates T cell activation and increases IL-2 production
- Potently degrades BTK in cynomolgus monkeys in vivo
- Leads to dose-proportional exposure in plasma
- Results in superior tumor growth inhibition in both WT TMD8 and C481S mutant xenograft models in mice
Medchemexpress LLC 2-Amino-5-methylpyrazine | 5521-58-4 | 99.7% | C5H7N3 | 1 G
2-Amino-5-methylpyrazine is an intermediate chemical compound primarily used in the synthesis of LPAR1 antagonists. This product is intended for research purposes only and not for patient use.
- Utilized as an intermediate for LPAR1 antagonist synthesis.
- Purity of 99.7%.
- Appears as a light brown to yellow solid.
- Highly soluble in DMSO.
- Store at 4°C, protected from light.
Medchemexpress LLC Thiazolidine, hydrochloride (1:1) | 14446-47-0 | 95.0% | C3H8CINS | 10 G
Thiazolidine hydrochloride is a white to yellow solid with a purity of 95.0% as determined by NMR. Its ¹H NMR Spectrum and MS are consistent with its structure, and it has a molecular formula of C3H8CINS with a molecular weight of 125.62. The product has been tested and complies with given specifications and is for research use only, not having been fully validated for medical applications.
- White to yellow solid appearance
- ¹H NMR spectrum consistent with structure
- Mass spectrometry consistent with structure
- Purity (NMR) of 95.0%
- Storage for powder: 3 years at -20°C, 2 years at 4°C
- Storage for in solvent: 6 months at -80°C, 1 month at -20°C
eMolecules Ambeed / Bz-Arg-OEt.HCl / 5g / 525085449 / A168972 / / 2645-08-1 / MFCD00012579 / 342.820 / C15H23ClN4O3
Ambeed / Bz-Arg-OEt.HCl / 5g / 525085449 / A168972 / / 2645-08-1 / MFCD00012579 / 342.820 / C15H23ClN4O3
Medchemexpress LLC Sodium decane-1-sulfonate | 13419-61-9 | MFCD00007526 | >98.0% | 244.33 | 10 G
Sodium decane-1-sulfonate is an anionic surfactant utilized for the analysis of organic small molecule compounds through HPLC and ion-pair liquid chromatography.
- Anionic surfactant
- Used for analysis of organic small molecule compounds
- Suitable for HPLC
- Suitable for ion-pair liquid chromatography
- Biochemical assay reagent
Chem-Impex International, Inc. Thiomorpholine | MFCD00005974 | 100G
Thiomorpholine, MFCD00005974, 100G
Medchemexpress LLC Tnfa Activ Modulator 3 Reconst | HY-160412-1MM/1ML RECONST
Tnfa Activ Modulator 3 Reconst