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LP-261 is a potent, orally active anti-mitotic agent. It demonstrates inhibition of in vitro tubulin polymerization with an EC50 of 3.2 μM. This compound has shown efficacy in inhibiting the growth of human non-small-cell lung tumors (NCI-H522) in vivo, making it a valuable tool for cancer research.
Potent anti-mitotic agent.
Orally active.
Inhibits in vitro tubulin polymerization.
Effective against human non-small-cell lung tumors (NCI-H522) in vivo.
Useful for cancer research applications.
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