Nourseothricin sulfate is a broad-spectrum antibiotic that inhibits protein biosynthesis in prokaryotic cells and strongly suppresses the growth of eukaryotes. It targets the outer membrane of Gram-negative bacteria and serves as a selective marker for various organisms, including bacteria, yeast, filamentous fungi, and plant cells.
- Broad-spectrum antibiotic
- Targets outer membrane of Gram-negative bacteria
- Serves as a selective marker for Fonsecaea pedrosoi
- Inhibits protein biosynthesis in prokaryotic cells
- Strongly suppresses growth of eukaryotes, such as fungi
- Sensitizes resistant Escherichia coli strains by eliminating outer membrane resistance
- Mixture of several Streptothricins (primarily D and F)
- Can create channels in the outer membrane