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Chemical. CAS 41575-94-4. Formula C6H12N2O4Pt. MW 371.3. Potent platinum-based antineoplastic agent. Analog of cisplatin Prod. No. AG-CR1-3590 with reduced nephrotoxicity and higher stability. Antitumor agent. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and inducing cell death. Interferes with cell division by mitosis. The damaged DNA elicits DNA repair mechanisms, which in turn activate apoptosis when repair is impossible. Apoptosis inducer. Enhances radiation-induced single-strand DNA breakage.
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Small-molecule replication protein A (RPA) inhibitor supplied as a 10 mM solution in DMSO (1 mL) for research use. Intended for in vitro studies of RPA-DNA interactions and combination effects with platinum-based chemotherapies.
Supplied as 10 mM solution in DMSO, 1 mL.
High purity (99.84%) suitable for biochemical assays.
Chemical formula C25H23ClIN3O4, molecular weight 591.83 g·mol⁻1.
Store frozen in solvent for stability (short- and long-term conditions apply).
Also available in multiple solid sizes for experimental flexibility.
For research use only; not for human or animal therapeutic use.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More