Other Solvents
Medchemexpress LLC Ketoprofen-d3 | 159490-55-8 | 99.4% | 5 MG
Ketoprofen-d3 is the deuterium labeled Ketoprofen. Ketoprofen (RP-19583) is a non-steroidal antiinflammatory agent, acting as a potent inhibitor of COX, with IC50s of 2 nM and 26 nM for COX-1 and COX-2 in human blood monocytes, respectively. It is for research use only. This compound can be used as a tracer and as an internal standard for quantitative analysis.
- Deuterium labeled compound
- Non-steroidal anti-inflammatory agent
- Potent inhibitor of COX-1 and COX-2
- Used as a tracer for quantitation during drug development
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Allopurinol | 315-30-0 | 100.0% | 1 ML
Allopurinol is a potent and orally active xanthine oxidase inhibitor with an IC50 value of 0.2-50 μM. It can be used in the research of hyperuricemia and gout. It decreases the expression of HIF-1α and HIF-2α protein. It also shows anti-depressant and anti-nociception activity, and anti-leishmanial effect.
- Potent and orally active xanthine oxidase inhibitor
- Can be used in the research of hyperuricemia and gout
- Decreases the expression of HIF-1α and HIF-2α protein
- Reduces angiogenesis traits of HUVEC cells
- Exhibits anti-depressant activity in mouse models
- Induces anti-nociception activity in mouse models
- Shows anti-leishmanial effect
Cambridge Isotope Laboratories VITAMIN K2 (MENAQUINONE MK-9) (5,6,7,8-D4, 2-METHYL-D3, 98%), 1 MG
VITAMIN K2 (MENAQUINONE MK-9) (5,6,7,8-D4, 2-METHYL-D3, 98%), 1 MG
Medchemexpress LLC Torsemide-d7 | 1189375-06-1 | 99.77% | 1 MG
Torsemide-d7 is the deuterium-labeled form of Torsemide, an orally active loop diuretic with anti-aldosterone and vasodilatory effects. It can be used in research for heart failure, renal disease, and hepatic cirrhosis. Deuterium substitution in drug molecules serves as a tracer for quantitation during drug development and can affect pharmacokinetic and metabolic profiles.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cayman Chemical SpermIdIn-d6 1mg
An internal standard for the quantification of spermidine by GC- or LC-MS
Medchemexpress LLC Sulbactam-d5 sodium | 1322625-44-4 | 99.9% | 500 UG
Sulbactam-d5 sodium is a deuterium-labeled form of Sulbactam sodium, a competitive, irreversible beta-lactamase inhibitor. It demonstrates antimicrobial activity against multidrug-resistant Acinetobacter calcoaceticus--Acinetobacter baumannii complex. Deuteration in drug molecules can impact pharmacokinetic and metabolic profiles, making this compound valuable for research.
- Functions as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Isotope-labeled compound
- Deuterium stable isotope-labeled inhibitor for in vivo cell experiments
- Applicable in therapeutic drug monitoring
Medchemexpress LLC Tetrabenazine-d6 | 1392826-25-3 | 98.2% | 5 MG
Tetrabenazine-d6 (Deutetrabenazine) is a deuterium-labeled Tetrabenazine, which is the first deuterium approved worldwide for the research of Huntington's disease, or other hyperkinetic movement disorders.
- Extend the half-life in vivo.
- Improve oral bioavailability.
- Improve metabolic characteristics.
- Improve drug safety.
- Preserve the therapeutic properties.
Medchemexpress LLC Clotrimazole-d10 | 23593-75-1 | 97.5% | 354.90 | 1 MG
Clotrimazole-d10 is a deuterated labeled form of Clotrimazole (HY-10882), which is an imidazole derivative known for its antifungal properties and as a CYP (cytochrome P450) inhibitor. This compound also exhibits antibacterial activity, making it versatile for various research applications.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Adenosine-d2 | 82741-17-1 | 99.6% | 5 MG
Adenosine-d2 is a deuterium-labeled adenosine, acting as a ubiquitous endogenous autacoid through four G protein-coupled receptors (A1, A2A, A2B, and A3). It affects almost all aspects of cellular physiology. Deuterium substitution is used in drug molecules as tracers for quantitative analysis and can influence pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Impacts cellular physiology
- Functions through G protein-coupled receptors: A1, A2A, A2B, and A3
Cambridge Isotope Laboratories VITAMIN K2 (MENAQUINONE MK-4) (5,6,7,8-D4, 2-METHYL-D3, 98%), 1 MG
VITAMIN K2 (MENAQUINONE MK-4) (5,6,7,8-D4, 2-METHYL-D3, 98%), 1 MG
Cambridge Isotope Laboratories L-SERINE (13C3, 99%; 15N, 99%), 0.1 G, 202407-34-9
L-SERINE (13C3, 99%; 15N, 99%), 0.1 G, 202407-34-9
Medchemexpress LLC Cefoperazone-d5 | 2410425-70-4 | 98.6% | 500 UG
Cefoperazone-d5 is a deuterium labeled semisynthetic cephalosporin with broad-spectrum antibacterial activity. This compound is suitable for use as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled Cefoperazone
- Semisynthetic cephalosporin with broad-spectrum antibacterial activity
- Suitable for use as a tracer
- Suitable for use as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Has the potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Anandamide-d8 | 924894-98-4 | 99.9% | 355.58 | 1 MG
Anandamide-d8 is a deuterated labeled version of Anandamide, an endocannabinoid that plays a role in modulating both neuronal and immune functions through CB1 and CB2 cannabinoid receptors. It can also activate other receptors such as PPARS, TRPV1, GPR18, and GPR55. Anandamide exhibits potential anti-fungal and anti-inflammatory activities and is being researched for its use in Alzheimer's disease (AD) and ulcerative colitis.
- Deuterated labeled Anandamide.
- Modulates neuronal and immune functions via CB1 and CB2 receptors.
- Activates receptors including PPARS, TRPV1, GPR18, and GPR55.
- Possesses potential anti-fungal and anti-inflammatory properties.
- Applicable for research in Alzheimer's disease (AD) and ulcerative colitis.
- Can be utilized as a tracer.
- Suitable for use as an internal standard for quantitative analysis by methods such as NMR, GC-MS, or LC-MS.
Cambridge Isotope Laboratories ETHYLENE GLYCOL D4, 98% 5G
ETHYLENE GLYCOL (D4, 98%)Chemical Purity98%.Chemical Formula HO(CD2)2OH.Labeled CAS# 2219-51-4