Other Solvents
Cayman Chemical Chlorzoxazon-d3 500ug
An internal standard for the quantification of chlorzoxazone by GC- or LC-MS
Cambridge Isotope Laboratories L-ASPARAGINE:H2O (15N2, 98%), 0.5 G, 287484-32-6
L-ASPARAGINE:H2O (15N2, 98%), 0.5 G, 287484-32-6
Medchemexpress LLC Alfacalcidol-d6 | 1641940-94-4 | C27H38D6O2 | 5 MG
Alfacalcidol-d6 is the deuterium labeled Alfacalcidol, functioning as a non-selective VDR activator. This compound can be utilized as a tracer and an internal standard for quantitative analysis methods such as NMR, GC-MS, or LC-MS.
- Deuterium-labeled compound
- Non-selective VDR activator
- Suitable for use as a tracer
- Functions as an internal standard for quantitative analysis
- Applicable in NMR, GC-MS, and LC-MS analytical techniques
Storage conditions: Powder: -20°C for 3 years, 4°C for 2 years. In solvent: -80°C for 2 years, -20°C for 1 year.
Medchemexpress LLC Baricitinib-d3 | 1564242-30-3 | C16H14D3N7O2S | 1 MG
Baricitinib-d3 is the deuterium labeled version of Baricitinib, a selective and orally bioavailable JAK1 and JAK2 inhibitor with IC50s of 5.9 nM and 5.7 nM, respectively. It is intended for research use only.
- Deuterium labeled Baricitinib
- Selective and orally bioavailable JAK1 and JAK2 inhibitor
- Suitable as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes for quantitation during drug development
- Deuteration can impact pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Repaglinide-d5 | 1217709-85-7 | C27H31D5N2O4 | 25 MG
Repaglinide-d5 is a deuterium-labeled variant of Repaglinide. Repaglinide acts as an insulin secretagogue, primarily used in the treatment of type-2 diabetes mellitus. It functions by enhancing the early phase of insulin secretion and increasing the overall amount of insulin released, which helps to reduce postprandial glucose levels.
- Used as a tracer.
- Serves as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
Medchemexpress LLC (±)-Fluoxetine-dd5 oxalate (phenyl-dd5) | 1219804-82-6 | C19H15D5F3NO5 | 1 MG
(±)-Fluoxetine-dd5 Oxalate (phenyl-dd5) is the deuterium labeled form of (±)-Fluoxetine Oxalate.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes of hydrogen, carbon, and other elements into drug molecules for quantitation during drug development
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Carboplatin-d4 | 41575-94-4 | 99.0% | 375.28 | 5 MG
Carboplatin-d4 is the deuterium labeled Carboplatin. It is a DNA synthesis inhibitor that binds to DNA, inhibits replication and transcription, and induces cell death. This compound is a derivative of CDDP and a potent anti-cancer agent, intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Rifabutin-d7 | 2747918-39-2 | 98.39% | 854.05 | 1 MG
Rifabutin-d7 is the deuterium labeled Rifabutin, a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. It inhibits DNA-dependent RNA polymerase and is suitable for laboratory centrifugation and storage. The compound can be used for research purposes only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 3-Methyladenine-d3 | 110953-39-4 | 99.0% | 152.17 | 5 MG
3-Methyladenine-d3 is a deuterium-labeled 3-Methyladenine. 3-Methyladenine (3-MA) acts as a PI3K inhibitor and is widely used as an autophagy inhibitor due to its inhibitory effect on class III PI3K.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Cetirizine-d4 | 1219803-84-5 | 98.0% | 392.91 | 1 MG
Cetirizine-d4 is a deuterium-labeled form of Cetirizine. Cetirizine is a second-generation antihistamine and a carboxylated metabolite of hydroxyzine. It acts as a specific, orally active, and long-acting histamine H1-receptor antagonist. The product demonstrates antiallergic properties and can inhibit eosinophil chemotaxis during allergic responses.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Emtricitabine-13C,15N2 | 1217820-69-3 | 250.23 | 500 UG
Emtricitabine-13C,15N2 is a 13C- and 15N-labeled Emtricitabine. It is a nucleoside reverse transcriptase inhibitor (NRTI) with an EC50 of 0.01 μM in PBMC cell and acts as an antiviral agent for the treatment of HIV infection. This product is for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Roflumilast-d4 | 1398065-69-4 | C17H10D4Cl2F2N2O3 | 1 MG
Roflumilast-d4 is a deuterium-labeled selective PDE4 inhibitor, primarily used for research. It can be utilized as a tracer or an internal standard for quantitative analysis by methods such as NMR, GC-MS, or LC-MS. Incorporating stable heavy isotopes into drug molecules, such as deuterium, aids in quantitation during drug development and can influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Roflumilast-d4 N-Oxide | 1794760-31-8 | C17H10D4Cl2F2N2O4 | 100 UG
Roflumilast-d4 N-Oxide is a deuterium-labeled version of Roflumilast, a selective PDE4 inhibitor. This compound is valuable as a tracer and internal standard for quantitative analysis in drug development, particularly due to the influence of deuteration on pharmacokinetic and metabolic profiles.
- Used as a tracer for quantitation
- Can be an internal standard for analytical methods
- Deuteration can influence pharmacokinetic and metabolic profiles
- Selective PDE4 inhibitor
Medchemexpress LLC Empagliflozin-d4 | 2749293-95-4 | C23H23D4ClO7 | 1 MG
Empagliflozin-d4 is deuterium labeled Empagliflozin, a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2. Deuterium substitution may affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Sacubitril-d4 | 1884269-07-1 | C24H25D4NO5 | 1 MG
Sacubitril-d4 is the deuterium-labeled version of Sacubitril, a potent Neprilysin (NEP) inhibitor (IC50 of 5 nM) and a component of the heart failure medicine LCZ696. This compound is valuable for research, serving as a tracer or an internal standard for quantitative analysis methods such as NMR, GC-MS, or LC-MS.
- Used as a tracer in research
- Functions as an internal standard for quantitative analysis
- Supports research in heart failure