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Sotalol-d6 hydrochloride is a deuterium labeled Sotalol hydrochloride. It acts as an orally active, non-selective competitive β-adrenergic receptor blocker and a potent antiarrhythmic agent, primarily used in the research of pediatric arrhythmias. The compound functions by blocking β-receptors and potassium KCNH2 channels.
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Apocynin-d3 is the deuterium-labeled form of Apocynin, a selective NADPH-oxidase inhibitor with an IC50 of 10 μM. This compound can be used for various applications:
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Demethoxycurcumin-d4 is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin (Curcumin II) is a major active curcuminoid with anti-inflammatory properties. It can be used as a tracer and an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Application as tracer
Internal standard for quantitative analysis
Deuterium substitution affects pharmacokinetic and metabolic profiles
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Thromboxane B2-D4 is the deuterium labeled Thromboxane B2. Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis, inducing arterial contraction and platelet aggregation.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Tropicamide-d3 is the deuterium labeled form of Tropicamide. Tropicamide is a selective M4 muscarinic acetylcholine receptor antagonist that produces short-acting mydriasis and cycloplegia when applied as eye drops. Deuterium substitution in drug molecules is of interest due to its potential impact on pharmacokinetic and metabolic profiles.
Can be used as a tracer
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Contains stable heavy isotopes for quantitation during drug development
Deuteration may affect pharmacokinetic and metabolic profiles of drugs
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Vericiguat-d3 hydrochloride is a deuterated Vericiguat with tracer functionality. Vericiguat is an orally available stimulator of guanylate cyclase. This compound can be used as a tracer or as an internal standard for quantitative analysis.
Used as a tracer
Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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Apalutamide-d4 is a deuterium labeled Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM.
This compound can be used as a tracer.
This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Maribavir-d6 TFA is a deuterium-labeled Maribavir, an orally active antiviral agent. It targets cytomegalovirus (CMV) by inhibiting protein kinase UL97, thereby preventing CMV DNA replication. This compound is suitable for various analytical techniques.
Used as a tracer.
Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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D-Glucose-13C2 is the 13C labeled D-Glucose, a monosaccharide and important carbohydrate in biology. It serves as a carbohydrate sweetener and a critical component of general metabolism, acting as a signaling molecule in relation to both cellular metabolic status and biotic and abiotic stress response.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Zonisamide-d4 is a deuterium-labeled version of Zonisamide, which is an inhibitor of the zinc enzyme carbonic anhydrase (CA). It demonstrates antiepileptic activity and is utilized in research for epilepsy, seizures, and Parkinson's disease. Deuterium labeling has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Pitavastatin-d4 is a deuterium-labeled form of Pitavastatin, a potent HMG-CoA reductase inhibitor. It is effective in inhibiting cholesterol synthesis and acts as an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer.