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Citric acid is a weak, naturally-occurring, organic acid and an intermediate in the citric acid cycle. Available in various quantities, purities, and reagent grades, it is used as a flavoring, preservative, chelating agent, cosmetics and drug component, etc.
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Tetrazine-Ph-acid is a tetrazine-containing small-molecule linker used for bioorthogonal inverse electron-demand Diels-Alder (iEDDA) click chemistry and in PROTAC linker synthesis. The molecule is carboxylic-acid functionalized, enabling standard coupling reactions and further derivatization for medicinal chemistry and chemical biology research applications.
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