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Gallic Acid

Gallic acid is a naturally-occurring trihydroxybenzoic acid. Available in various quantities, it is an astringent, a cyclooxygenase 2 inhibitor, an antioxidant, an antineoplastic agent, a weak carbonic anhydrase inhibitor, an apoptosis inducer, etc.

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1

Bergenin 98.0+%, TCI America™

CAS: 477-90-7 Molecular Formula: C14H16O9 Molecular Weight (g/mol): 328.273 MDL Number: MFCD00133120 InChI Key: YWJXCIXBAKGUKZ-HJJNZUOJSA-N PubChem CID: 66065 ChEBI: CHEBI:69499 IUPAC Name: (2R,3S,4S,4aR,10bS)-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one SMILES: COC1=C(C=C2C(=C1O)C3C(C(C(C(O3)CO)O)O)OC2=O)O

PubChem CID 66065
CAS 477-90-7
Molecular Weight (g/mol) 328.273
ChEBI CHEBI:69499
MDL Number MFCD00133120
SMILES COC1=C(C=C2C(=C1O)C3C(C(C(C(O3)CO)O)O)OC2=O)O
IUPAC Name (2R,3S,4S,4aR,10bS)-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one
InChI Key YWJXCIXBAKGUKZ-HJJNZUOJSA-N
Molecular Formula C14H16O9
2

eMolecules​ 329932-55-0 | Medchem Express | FM19G11 | 5mg | 722714433 | HY-15672 | MFCD01174289 | 463.402 | C23H17N3O8

Ambeed | 5-Bromo-7-nitroindoline | 5g | 490559644 | A394432 | 80166-90-1 | MFCD00005708 | 243.060 | C8H7BrN2O2

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3

Medchemexpress LLC ACBI1 | 2375564-55-7 | 99.9% | 50 MG
SDP

ACBI1 is a potent and cooperative degrader of SMARCA2, SMARCA4, and PBRM1, functioning as a PROTAC degrader that demonstrates anti-proliferative activity and induces apoptosis. It has DC50s of 6, 11, and 32 nM for SMARCA2, SMARCA4, and PBRM1, respectively.

  • Targets VHL, SMARCA2, SMARCA4, and PBRM1
  • Exhibits antiproliferative activity against human MV4-11 cells (IC50 of 28 nM)
  • Induces apoptosis in SK-MEL-5 cells
  • Soluble in DMSO at ≥ 100 mg/mL (106.83 mM)
  • Formulations available for in vivo use with 10% DMSO, 40% PEG300, 5% Tween-80, 45% Saline or 10% DMSO, 90% Corn Oil

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