Pamoic Acid
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Medchemexpress LLC Pamoic acid | 130-85-8 | 99.7% | 388.38 | 1 ML
Pamoic acid (Embonic acid) is a potent GPR35 agonist with an EC50 of 79 nM. It exhibits neuroprotective and anti-inflammatory properties.
- Potent GPR35 agonist
- Exhibits neuroprotective properties
- Exhibits anti-inflammatory properties
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Medchemexpress LLC Pamoic acid (Embonic acid) | 130-85-8 | 99.7% | 388.38 | 1 G
Pamoic acid (Embonic acid) is a potent GPR35 agonist with an EC50 of 79 nM. It exhibits neuroprotective and anti-inflammatory properties. GPR35 activation by Pamoic acid may increase the phosphorylation of ERK1/2, which suppresses NF-κB-dependent inflammatory genes.
- Potent GPR35 agonist with an EC50 of 79 nM.
- Exhibits neuroprotective properties.
- Exhibits anti-inflammatory properties.
- Activates GPR35 to increase phosphorylation of ERK1/2.
- Suppresses NF-κB-dependent inflammatory genes.
- Reduces infarct size in a GPR35 dependent manner.
- Increases noninflammatory Ly-6CLo monocytes/macrophages in ischemic brain.
- Reduces neutrophil counts.