Tiglic acid is a monocarboxylic unsaturated organic acid that can be isolated from croton oil. It agonizes FFA2, upregulates PYY expression, and its derivatives have anti-inflammatory activity. It is used in the research of obesity, diabetes, and inflammatory diseases.
- Appearance: Solid, white to light yellow
- Structure classification: Ketones, aldehydes, acids
- Initial source: Plants Verbenaceae Lantana camara Linn.
- Endogenous metabolite: Yes
- Targets: Free Fatty Acid Receptor, Neuropeptide Y Receptor
- Pathway: GPCR/G Protein, neuronal signaling
- Storage (powder): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 2 years, -20°C for 1 year
- Solubility (in vitro): DMSO 100 mg/mL, H2O 5 mg/mL