Homovanillic acid (Vanilacetic acid) is a dopamine metabolite that has been associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency. This product is classified under Monophenols, Ketones, Aldehydes, Acids, and Phenols, acting as both an endogenous metabolite and a drug metabolite.
- Relevant to disease markers and various research fields including metabolic disease, nervous system disorder, immune system disorder, and endocrine diseases.
- Increases presynaptic membrane protein SYN1 in HT22 and rat hippocampal neurons, protecting synaptic structure.
- Inhibits the degradation of autophagy marker proteins LC3 and SQSTM1/p62, reducing autophagosome formation.