Acyl bromides
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Medchemexpress LLC Cetrimonium bromide | 57-09-0 | 98.0% | 500 MG
Cetrimonium bromide (CTAB) is a quaternary ammonium, orally active cationic surfactant. It exhibits toxicity and anticancer effects. It inhibits cell migration and invasion by modulating canonical and non-canonical TGF-β signaling pathways. Cetrimonium bromide can also be used for DNA extraction.
- Cationic surfactant
- Exhibits toxicity and anticancer effects
- Inhibits cell migration and invasion by modulating canonical and non-canonical TGF-β signaling pathways
- Can be used for DNA extraction
- Does not affect growth of SK-HEP-1 cells at 1-5 μM for 24 hours
- Attenuates cellular migration and invasion of SK-HEP-1 cells at 5 μM for 16-24 hours
- Inhibits protein expression of MMP-2 and MMP-9, increases TIMP-1 and TIMP-2, and restrains Rac1, cdc42, and RhoA in SK-HEP-1 cells at 5 μM for 24 hours
- Induces apoptosis in human head and neck cancer (HNC) cells at 5 μM for 12-72 hours
