Cyclohexyl halides
Search Within Results
1
–
1
of
1
results
1
Medchemexpress LLC (4S)-GLP-1 receptor agonist 14 | 2758659-09-3 | 99.6% | 880.94 | 1 ML
(4S)-GLP-1 receptor agonist 14 is a potent and orally active GLP-1 receptor agonist with an EC50 ≤ 20 nM. It can be used for research on diabetes, obesity, metabolic diseases, cardiovascular diseases, liver diseases, nonalcoholic steatohepatitis (NASH), and other diseases associated with the GLP-1 receptor. It exhibits good PK parameters in rats.
- Potent and orally active GLP-1 receptor agonist
- EC50 ≤ 20 nM
- Can be used for research on diabetes, obesity, metabolic diseases, cardiovascular diseases, liver diseases, nonalcoholic steatohepatitis (NASH), and other diseases associated with the GLP-1 receptor.
- Inhibits OATP1B1 with an IC50 < 1 μM in HEK293 cells.
- Exhibits good PK parameters in rats (5 mg/kg, p.o., single dose), with Cmax of 1700 ng/mL, AUC of 10193 ng·h/mL, and F of 90%.
