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Medchemexpress LLC (4S)-GLP-1 receptor agonist 14 | 2758659-09-3 | 99.6% | 880.94 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY16477410MM/1ML

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(4S)-GLP-1 receptor agonist 14 is a potent and orally active GLP-1 receptor agonist with an EC50 ≤ 20 nM. It can be used for research on diabetes, obesity, metabolic diseases, cardiovascular diseases, liver diseases, nonalcoholic steatohepatitis (NASH), and other diseases associated with the GLP-1 receptor. It exhibits good PK parameters in rats.

  • Potent and orally active GLP-1 receptor agonist
  • EC50 ≤ 20 nM
  • Can be used for research on diabetes, obesity, metabolic diseases, cardiovascular diseases, liver diseases, nonalcoholic steatohepatitis (NASH), and other diseases associated with the GLP-1 receptor.
  • Inhibits OATP1B1 with an IC50 < 1 μM in HEK293 cells.
  • Exhibits good PK parameters in rats (5 mg/kg, p.o., single dose), with Cmax of 1700 ng/mL, AUC of 10193 ng·h/mL, and F of 90%.

Catalog No. 50-003-91657


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