Halomethanes
![Medchemexpress LLC 3-((3,4-dichlorophenyl)carbamoyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid | 199735-88-1 | MFCD00167693 | 98.2% | 326.17 g·mol⁻¹ | C15H13Cl2NO3 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000242145.png-250.jpg)
Medchemexpress LLC 3-((3,4-dichlorophenyl)carbamoyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid | 199735-88-1 | MFCD00167693 | 98.2% | 326.17 g·mol⁻¹ | C15H13Cl2NO3 | 100 MG
CADD522 is a small-molecule inhibitor of RUNX2-DNA binding used for laboratory research. It downregulates RUNX2-mediated transcription, exhibits an IC50 of about 10 nM, and has shown inhibition of primary tumor growth and experimental metastasis in preclinical studies. Chemical identifiers include CAS 199735-88-1, formula C15H13Cl2NO3, and molecular weight 326.17 g·mol⁻¹.
- High purity (98.2%).
- Potent RUNX2-DNA binding inhibition (IC50 ≈ 10 nM).
- Suitable for in vitro and preclinical research applications.
- White to off-white solid, soluble in DMSO as a 10 mM solution.
- Available as a 100 mg solid package.
- For research use only; not for human or diagnostic use.
eMolecules 93547-88-7 | Ambeed | tert-Butyldiphenylsilanol | 1g | 721418446 | A1524304 | 256.42 | C16H20OSi
Ambeed | tert-Butyldiphenylsilanol | 1g | 721418446 | A1524304 | 93547-88-7 | 256.420 | C16H20OSi
eMolecules 593-71-5 | Chloroiodomethane | Apollo Scientific | MFCD00001078 | 176.380 | CH2ClI | 97.000 | ClCI | 25g | 771340365
Chloroiodomethane | Apollo Scientific | 593-71-5 | MFCD00001078 | 176.380 | CH2ClI | 97.000 | ClCI | 25g | 771340365
eMolecules 593-71-5 | Chloroiodomethane | Apollo Scientific | MFCD00001078 | 176.380 | CH2ClI | 97.000 | ClCI | 500g | 771340367
Chloroiodomethane | Apollo Scientific | 593-71-5 | MFCD00001078 | 176.380 | CH2ClI | 97.000 | ClCI | 500g | 771340367
Medchemexpress LLC Ethanaminium, 2-hydroxy-N-(iodomethyl)-N,N-dimethyl-, iodide | 28508-22-7 | MFCD20489393 | 98.0% | 356.97 g/mol | C5H13I2NO | 500 MG
Iodocholine iodide is a quaternary ammonium iodide used as a non-radioactive analogue of C-11 choline and as a metabolizable catalyst for free-radical polymerization. Supplied as a solid reagent, it is intended for biochemical assays, radiochemistry standards, and polymer chemistry research; analytical documentation (COA, SDS, NMR, LCMS) is available.
- Non-radioactive standard for choline radiochemistry.
- Metabolizable catalyst for free-radical polymerization.
- High purity suitable for analytical and research applications.
- Available in multiple laboratory pack sizes for flexible use.
- Accompanied by COA, SDS, NMR, and LCMS documentation.
![Medchemexpress LLC N-[5-({2-[(cyclopropylcarbonyl)amino]-imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-... | 1005780-62-0 | MFCD23160045 | 99.7% | 445.47 g·mol⁻1 | C23H23N7O3 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000287464.png-250.jpg)
Medchemexpress LLC N-[5-({2-[(cyclopropylcarbonyl)amino]-imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-... | 1005780-62-0 | MFCD23160045 | 99.7% | 445.47 g·mol⁻1 | C23H23N7O3 | 10 MG
TAK-593 is a small-molecule tyrosine kinase inhibitor originally developed by Takeda Pharmaceutical Company. It potently inhibits vascular endothelial growth factor receptors and platelet-derived growth factor receptors and has demonstrated anti-angiogenic and antitumor activity in preclinical studies. Reported biochemical IC50 values include 3.2 nM (VEGFR1), 0.95 nM (VEGFR2), 1.1 nM (VEGFR3), 4.3 nM (PDGFRα), and 13 nM (PDGFRβ).
- Potent VEGFR and PDGFR inhibition (VEGFR2 IC50 ≈ 0.95 nM).
- High biochemical selectivity toward receptor tyrosine kinases.
- Reported molecular formula C23H23N7O3 and molecular weight ≈ 445.47 g·mol⁻1.
- High purity, typically reported as 99.66% by supplier.
- Provided with analytical documentation such as LC-MS.
- Suitable for preclinical studies of angiogenesis and tumor biology.
Medchemexpress LLC Methylene blue | 61-73-4 | MFCD00012111 | 95.0% | C16H18ClN3S | 100 MG
Methylene blue is an inhibitor of guanylyl cyclase (sGC), monoamine oxidase A (MAO-A), and NO synthase (NOS). It acts as a vasopressor and is commonly used as a dye in various medical procedures. This REDOX cycling compound is capable of crossing the blood-brain barrier and is also a Tau aggregation inhibitor. It helps reduce cerebral edema, mitigate microglial activation, and decrease neuroinflammation.
- Inhibits guanylyl cyclase (sGC), monoamine oxidase A (MAO-A), and NO synthase (NOS)
- Acts as a vasopressor
- Commonly used as a dye in medical procedures
- Impacts prepulse inhibition through the nitric oxide synthase/guanylate cyclase signaling pathway
- Functions as a REDOX cycling compound
- Capable of crossing the blood-brain barrier
- Acts as a Tau aggregation inhibitor
- Helps reduce cerebral edema
- Mitigates microglial activation
- Decreases neuroinflammation
Medchemexpress LLC CHI-KAT8i5 | 2839860-29-4 | 98.00% | 523.69 | 5 MG
CHI-KAT8i5 is a selective, orally active KAT8 inhibitor that induces cancer cell apoptosis and suppresses esophageal squamous cell carcinoma (ESCC) growth by targeting the KAT8/c-Myc signaling pathway. It demonstrates high specificity and anti-proliferative effects in vitro and in vivo.
- Selective, orally active KAT8 inhibitor
- High specificity; does not bind to other HAT family proteins
- Induces cancer cell apoptosis
- Suppresses esophageal squamous cell carcinoma (ESCC) growth
- Targets KAT8/c-Myc signaling pathway
- Demonstrates in vitro anti-proliferative effects against KYSE 30 and KYSE 150 cells
- Represses NPM1 and PPAT transcript expression; decreases H4K16ace and c-Myc levels
- Effective in vivo in suppressing ESCC tumor growth
- Reduces Ki-67, c-Myc expression, and H4K16ace levels in vivo
TARGETMOL CHEMICALS INC Ilmetropium iodide 50MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes.Ilmetropium iodide is a bronchodilator. Purity 98.01%
TARGETMOL CHEMICALS INC Isopropamide Iodide 100MG
Also available in 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. Isopropamide iodide is a long-acting anticholinergic drug used for peptic ulcers and other gastrointestinal disorders, and as a muscarinic receptor antagonist for diseases affecting cognition [including Alzheimer's disease]. Purity 99.91%
TARGETMOL CHEMICALS INC TAK-593 10MG
Also available in 1 mL, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRalpha, and PDFGRbeta, respectively). Purity 99.18%
Medchemexpress LLC Beperidium iodide | 86434-57-3 | 100.0% | 527.44 g·mol⁻¹ | C23H34IN3O3 | 10 MG
Beperidium iodide is a research-grade muscarinic acetylcholine receptor antagonist reported with a pA2 of 7.93. Supplied as the iodide salt, it is intended for laboratory research use only and provides a defined, high-purity material for receptor pharmacology studies.
- High purity suitable for research applications (reported 99.97%).
- Identified by CAS 86434-57-3 for unambiguous chemical identification.
- Chemical formula C23H34IN3O3 and molecular weight 527.44 g·mol⁻¹.
- Available in small mass quantities for assay development and screening.
- Provided as the iodide salt optimized for receptor-binding studies.
Medchemexpress LLC Inaxaplin | 2446816-88-0 | 99.4% | 417.38 g/mol | C21H18F3N3O3 | 5 MG
Inaxaplin (VX-147) is a small-molecule apolipoprotein L1 (APOL1) function inhibitor used in research on APOL1-mediated kidney disease. Supplied for research use only, the compound is characterized for in vitro and translational studies and is available as a high-purity solid and as a DMSO solution for biochemical and cell-based assays.
- Potent APOL1 inhibition suitable for mechanism-of-action studies.
- Intended for research use only and not for clinical use.
- Available as a high-purity solid and as a 10 mM DMSO solution.
- High reported purity supports reproducible experimental results.
- Suitable for biochemical, cellular, and translational research on kidney disease.
eMolecules 593-71-5 | CHLOROIODOMETHANE | AstaTech | MFCD00001078 | 176.380 | CH2ClI | 95.000 | ClCI | 25g | 718057679
CHLOROIODOMETHANE | AstaTech | 593-71-5 | MFCD00001078 | 176.380 | CH2ClI | 95.000 | ClCI | 25g | 718057679
eMolecules 75-11-6 | Diiodomethane | Oakwood Chemical | MFCD00001079 | 267.836 | CH2I2 | 98.000 | ICI | 10g | 537691334
Diiodomethane | Oakwood Chemical | 75-11-6 | MFCD00001079 | 267.836 | CH2I2 | 98.000 | ICI | 10g | 537691334