Halomethanes
![Medchemexpress LLC 2-Heptenoic acid, 7-[[1-[2-[(2-ethylbutyl)amino]-2-oxoethyl]-1,2-dihydro-2-oxo-3-pyridinyl]amino]-6-[[(1-me... | 1542132-88-6 | 100.0% | 528.60 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000386127-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2-Heptenoic acid, 7-[[1-[2-[(2-ethylbutyl)amino]-2-oxoethyl]-1,2-dihydro-2-oxo-3-pyridinyl]amino]-6-[[(1-me... | 1542132-88-6 | 100.0% | 528.60 | 5 MG
Vilagletistat (ZED-1227) is a specific and orally active transglutaminase 2 (TG2) inhibitor, with an IC50 of 45 nM. It effectively blocks inflammation-induced TG2 expression and activity, making it suitable for research into celiac disease (CeD).
- Specific and orally active TG2 inhibitor
- IC50 of 45 nM against TG2
- Blocks inflammation-induced TG2 expression and activity
- Suitable for research of celiac disease (CeD)
- Shows no cytotoxic activity in Huh7 and CaCo2 cells
- Inhibits TG2 in small intestinal mucosa both in vitro and in vivo
Medchemexpress LLC Aryl Hydrocarbon Receptor Antibody (YA610) | Predicted band size: 96 kDa; Observed band size: 105 kDa | 10 UL
Aryl Hydrocarbon Receptor Antibody (YA610) is a rabbit-derived, non-conjugated IgG monoclonal antibody targeting the Aryl Hydrocarbon Receptor. It plays a critical role in cellular adaptation to environmental, dietary, microbial, and metabolic cues, influencing development, immunity, and cancer. For research use only.
- Host: Rabbit
- Clonality: Recombinant, monoclonal
- Species reactivity: Human
- Immunogen: Synthetic human Aryl Hydrocarbon Receptor peptide (AA range: 735-775)
- Applications: WB (1:1000-1:2000), ICC/IF (1:100-1:500)
- Sensitivity: Endogenous
- Conjugation: Non-conjugated
- Isotype: IgG
- Appearance: Liquid
- Formulation: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol, 0.05% Sodium Azide
- Storage: -20°C for 1 year; avoid freeze/thaw cycles
- Shipping: Blue ice
Medchemexpress LLC Aryl Hydrocarbon Receptor Antibody (YA610) | Predicted: 96 kDa; Observed: 105 kDa | 100 UL
Aryl Hydrocarbon Receptor Antibody (YA610) is a rabbit-derived, non-conjugated IgG monoclonal antibody. It targets the Aryl Hydrocarbon Receptor and is protein A affinity purified. This antibody is for research use only.
- Rabbit-derived
- IgG monoclonal antibody
- Targets Aryl Hydrocarbon Receptor
- Protein A affinity purified
- Non-conjugated
- Reactive with human samples
- Suitable for Western Blot (WB) and Immunocytochemistry/Immunofluorescence (ICC/IF) applications
Medchemexpress LLC (-)-Alkannin | 517-88-4 | MFCD00189414 | 99.9% | 288.30 g·mol⁻1 | C16H16O5 | 10 MG
(-)-Alkannin is a naturally occurring naphthoquinone used in research as an apoptosis inducer that can arrest the cell cycle. It is supplied as a high-purity solid suitable for biochemical and cell-based studies, provided in small packaging for limited-scale experiments.
- Apoptosis inducer and cell cycle arrest agent.
- High purity suitable for analytical and biological assays.
- Solid, brown to red appearance for easy handling.
- Available in small package sizes (including 10 mg) for pilot studies.
- Recommended storage conditions provided for powder and solutions.
eMolecules Pharmablock / 1-(methylaminomethyl)cyclobutanol / 25mg / 587659667 / PBU6011 / 0.000 / 1461706-88-6 / MFCD24076247 / 115.176 / C6H13NO
Pharmablock / 1-(methylaminomethyl)cyclobutanol / 25mg / 587659667 / PBU6011 / 0.000 / 1461706-88-6 / MFCD24076247 / 115.176 / C6H13NO
Medchemexpress LLC 2-Ethylbutyric acid | 88-09-5 | 116.16 | 500 MG
2-Ethylbutyric acid is a volatile fatty acid known for its phytotoxicity. It serves as an internal standard in milk and dairy products, aids in calibrating fecal VFA standards, and is used in embryonic development research.
- Exhibits acute phytotoxicity in seed germination bioassays.
- Shows teratogenic activity in pregnant mice at 600 mg/kg (s.c.; single dose).
- No developmental toxicity in pregnant Sprague-Dawley rats at 150-200 mg/kg (p.o.; once daily; gestation days 6 to 15), with a No Observed Adverse Effect Level (NOAEL) of 200 mg/kg.
- EC50 of 33.74 μM for reduction of propionyl-CoA in human hepatocytes.
Apexbio Technology LLC 360A iodide 737763-37-0 5mg
360A iodide (CAS 737763-37-0) is a 2 6-pyridine-dicarboxamide derivative that acts as a selective ligand for G-quadruplex DNA structures By stabilizing telomeric G-quadruplexes 360A inhibits telomerase activity and induces alterations in cell cycle progression notably causing S-phase accumulation in ATM-proficient EBV-lymphocytes Its mechanism of action involves promoting sister telomere fusions via DNA-PKcs-dependent non-homologous end joining (NHEJ) as well as triggering NHEJ and homologous recombination (HR) pathways at telomeres which disrupt mitotic progression 360A has been shown to preferentially bind telomeric G-quadruplex DNA over duplex DNA and to delay growth in HT1080 tumor cells This compound is valuable for investigating telomere biology DNA damage response and G-quadruplex-mediated genomic stability
Sigma Aldrich Fine Chemicals Biosciences Dibromomethane-d2 >=99 atom % D, >=99% (CP), contains copper as stabilizer | 22117-86-8 | MFCD00000169 | 5G
Dibromomethane-d2 >=99 atom % D, >=99% (CP), contains copper as stabilizer | Purity: >=99% (CP) | Mol Wt: 175.85 | 22117-86-8 | MFCD00000169 | 5G
