Aryl bromides

Medchemexpress LLC 6-[(4-bromo-2-thienyl)methoxy]-9H-purin-2-amine | 192441-08-0 | MFCD23703756 | >=98.0% | 326.17 g·mol⁻¹ | C10H8BrN5OS | 5 MG

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Lomeguatrib is a potent O6-methylguanine-DNA methyltransferase (MGMT) inhibitor used in research to sensitize cells to alkylating agents; it shows low-nanomolar activity in biochemical and cell assays.

• Potent MGMT inhibitor (IC50 9 nM cell-free; ~6 nM in MCF-7 cells).
• Used to sensitize cells to alkylating agents in research applications.
• Available in small research pack sizes: 1 mg, 5 mg, 10 mg.
• Molecular weight 326.17 g·mol⁻¹; chemical formula C10H8BrN5OS.
• Powder storage: -20°C (up to 3 years) or 4°C (up to 2 years); in solvent: -80°C (up to 2 years).
• Supplied as a research-grade small molecule for in vitro studies.