AG-205 is a small-molecule inhibitor of progesterone receptor membrane component-1 (PGRMC1) provided for research use. It displays anti-mitotic, anti-migratory, and anti-invasive activity, modulates apoptosis and cell-cycle regulation, and influences expression of genes involved in cholesterol biosynthesis and steroidogenesis.
- PGRMC1 inhibitor activity relevant for cell-signaling studies.
- Anti-mitotic, anti-migratory, and anti-invasive effects in cancer cell models.
- Modulates apoptosis and cell-cycle regulatory pathways.
- Alters expression of genes involved in cholesterol biosynthesis and steroidogenesis.
- High purity (99%) suitable for research applications.
- Stable as a powder under recommended cold storage conditions.