Indanes
Apexbio Technology LLC MCC950 sodium(Synonyms: CP-456773 sodium, CRID3 sodium, MCC-950 sodium, MCC950 sodium salt), 10mg, CAS: 256373-96-3.
MCC950 sodium (CAS 256373-96-3) is a selective small-molecule inhibitor targeting the NOD-like receptor family protein 3 (NLRP3) inflammasome MCC950 sodium inhibits NLRP3 activation in murine bone marrow-derived macrophages (BMDMs) with an IC50 of 7 5 nM and demonstrates comparable selectivity and potency in human monocyte-derived macrophages (HMDMs) It specifically blocks both canonical and noncanonical activation pathways without affecting other inflammasomes such as AIM2 NLRC4 and NLRP1 Due to its selectivity MCC950 sodium is valuable in investigating NLRP3-associated inflammatory and autoimmune conditions
eMolecules 6-Chloro-indan-1-ylamine | 67120-38-1 | MFCD07373938 | 5g
J & W PharmLab LLC | 6-Chloro-indan-1-ylamine | 5g | 289350889 | 20R0819 | 98.000 | 67120-38-1 | MFCD07373938 | 167.640 | C9H10ClN
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eMolecules (Indan-5-yloxy)-acetic acid | 1878-58-6 | 5G | Purity: 96%
Combi-Blocks | (Indan-5-yloxy)-acetic acid | 5G | 1878-58-6 | MFCD01672404
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eMolecules Indan-2,5-diamine dihydrochloride | 131742-56-8 | | 1g
J&W PharmLab LLC | Indan-2,5-diamine dihydrochloride | 1g | 592892507 | 20R1728S | 98.000 | 131742-56-8 | | 221.130 | C9H14Cl2N2
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Accela Chembio Inc (1r | 2s)-(+)-cis-1-amino-2-indanol | 25g | 136030-00-7 | MFCD00216656 | 97% | Shelf Life: 540 Days |
(1r | 2s)-(+)-cis-1-amino-2-indanol | 25g | 136030-00-7 | MFCD00216656 | 97% | Shelf Life: 540 Days |
eMolecules 6-Bromo-indan-1-ylamine hydrochloride | 1199782-92-7 | MFCD08544168 | 1g
J & W PharmLab LLC | 6-Bromo-indan-1-ylamine hydrochloride | 1g | 508862480 | 20R0816S | 98.000 | 1199782-92-7 | MFCD08544168 | 248.550 | C9H11BrClN
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eMolecules Indan-1,6-diamine dihydrochloride | 2387535-17-1 | | 1g
J & W PharmLab LLC | Indan-1,6-diamine dihydrochloride | 1g | 491380145 | 20R1789S | 96.000 | 2387535-17-1 | | 221.130 | C9H14Cl2N2
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eMolecules (R)-1-Amino-indan-4-ol hydrochloride | 2097073-21-5 | MFCD30735820 | 1g
J & W PharmLab LLC | (R)-1-Amino-indan-4-ol hydrochloride | 1g | 347416463 | 20R0877S | 96.000 | 2097073-21-5 | MFCD30735820 | 185.650 | C9H12ClNO
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eMolecules cis-1-Methoxy-2-indanol | 56175-44-1 | MFCD01547311 | 1g
Oakwood Chemical | cis-1-Methoxy-2-indanol | 1g | 537709731 | 103211 | | 56175-44-1 | MFCD01547311 | 164.204 | C10H12O2
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Apexbio Technology LLC Ramelteon(Synonyms: Rozerem, TAK-375, Ramelteon, Melatonin receptor agonist, MT1/MT2 agonist), 5mg, CAS: 196597-26-9.
Ramelteon (CAS 196597-26-9) is a potent orally active agonist selective for MT1 and MT2 melatonin receptors Structurally characterized by its S-enantiomer and ether functional group ramelteon exhibits high binding affinity toward MT1 and MT2 receptors with reported Ki values of 14 pM and 112 pM respectively whereas affinity for the MT3 receptor is considerably lower (Ki 2650 nM) By activating MT1 and MT2 receptors ramelteon suppresses cAMP production in human cells expressing these receptors with IC50 values of 21 2 pM/L (MT1) and 53 4 pM/L (MT2) Given its receptor selectivity and minimal side-effect profile ramelteon is frequently utilized in research investigating circadian rhythms and sleep disorders