Indanes
Apexbio Technology LLC Ramelteon(Synonyms: Rozerem, TAK-375, Ramelteon, Melatonin receptor agonist, MT1/MT2 agonist), 5mg, CAS: 196597-26-9.
Ramelteon (CAS 196597-26-9) is a potent orally active agonist selective for MT1 and MT2 melatonin receptors Structurally characterized by its S-enantiomer and ether functional group ramelteon exhibits high binding affinity toward MT1 and MT2 receptors with reported Ki values of 14 pM and 112 pM respectively whereas affinity for the MT3 receptor is considerably lower (Ki 2650 nM) By activating MT1 and MT2 receptors ramelteon suppresses cAMP production in human cells expressing these receptors with IC50 values of 21 2 pM/L (MT1) and 53 4 pM/L (MT2) Given its receptor selectivity and minimal side-effect profile ramelteon is frequently utilized in research investigating circadian rhythms and sleep disorders
Medchemexpress LLC HY-13951 10mg Medchemexpress, ICI 118,551 (hydrochloride) CAS:72795-01-8 Purity:>98%
Medchemexpress, HY-13951 10mg ICI 118,551 (hydrochloride) CAS:72795-01-8 ICI 118,551 (hydrochloride) is a highly selective β2 adrenergic receptor antagonist, with Kis of 0.7, 49.5 and 611 nM for β2, β1 and β3 receptors, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Alkali Scientific Methylene Blue Trihydrate, 100 Grams
Methylene Blue Trihydrate, 100g is a dye used primarily in biological staining to visualize cellular structures in various specimens. The dye binds to acidic components within cells, highlighting structures such as the nucleus and certain organelles. Methylene Blue is commonly used in microbiology for staining bacterial cells, as well as in histology and hematology for the examination of tissues and blood smears. This 100g pack size is ideal for laboratories conducting routine staining or requiring large amounts of dye for repeated experiments. It is a reliable stain for use in research studies, clinical diagnostics, and educational settings, providing clear and consistent results in cell viability and morphology analysis.
eMolecules 1618636-37-5 | Medchem Express | Ozanimod (hydrochloride) | 5mg | 789373656 | HY-12288A | 440.93 | C23H25ClN4O3
ChemScene | (S)-2-Amino-2-(4-bromo-2-methylphenyl)ethan-1-ol hydrochloride | 100mg | 712793887 | CS-0168723 | 2250243-40-2 | 266.560 | C9H13BrClNO
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eMolecules (R,S)-Boc-1-aminoindane-1-carboxylic acid | 214139-26-1 | 1G | Purity: 97%
Combi-Blocks | (R,S)-Boc-1-aminoindane-1-carboxylic acid | 1G | 214139-26-1 | MFCD00800596
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Apexbio Technology LLC GDC-0879(Synonyms: AR-00341677, GDC0879, GDC 0879, G-0879, G0879), 5mg, CAS: 905281-76-7.
GDC-0879 (CAS 905281-76-7) is a selective inhibitor of B-Raf kinase targeting the Raf/MEK/ERK signaling cascade implicated in tumorigenesis It specifically inhibits B-Raf harboring the V600E mutation demonstrating IC50 values of 0 13 nM against purified mutant B-Raf and 63 nM for phosphorylated ERK in MALME-3M cells In vitro assays using V600E mutant cell lines (A375 melanoma Colo205 colorectal cancer) illustrate the compound s selectivity towards B-Raf and related C-Raf kinases In mouse xenografts expressing human BRAFV600E tumors GDC-0879 treatment results in sustained ( 90%) inhibition of ERK phosphorylation and reduced tumor progression highlighting its research value in oncology studies involving Raf pathway modulation
Medchemexpress LLC (1S,2R)-1-Aminoindan-2-ol | 126456-43-7 | 149.19 | 250 G
(1S,2R)-1-Aminoindan-2-ol is a chiral resolving agent that efficiently resolves various racemic 2-arylalkanoic acids. It precisely controls the stereostructure of products in asymmetric syntheses and can also be used in the synthesis of HIV protease inhibitors.
- Chiral resolving agent
- Efficiently resolves various racemic 2-arylalkanoic acids
- Precisely controls stereostructure of products in asymmetric syntheses
- Can be used in the synthesis of HIV protease inhibitors
Apexbio Technology LLC Atipamezole hydrochloride 104075-48-1 10mg
Atipamezole hydrochloride (CAS 104075-48-1) is a potent antagonist of 2-adrenergic receptors exhibiting a Ki value of 1 6 nM By selectively inhibiting the 2-adrenergic signaling pathway it modulates neurotransmitter release within the central nervous system Atipamezole hydrochloride is frequently utilized in neuroscience research to investigate mechanisms of noradrenergic regulation with established applications in reversal of sedative effects and evaluation of cognitive function
Accela Chembio Inc 1-aminoindane Hydrochloride | 5g | 70146-15-5 | MFCD00054294 | 97+% | Shelf Life: 1800 Days | Light Sensitive/n2
1-aminoindane Hydrochloride | 5g | 70146-15-5 | MFCD00054294 | 97+% | Shelf Life: 1800 Days | Light Sensitive/n2
eMolecules 168649-23-8 | Medchem Express | 5-Ph-IAA | 5mg | 587658681 | HY-134653 | 251.285 | C16H13NO2
Medchem Express | Terameprocol | 5mg | 722713989 | HY-10447 | 24150-24-1 | MFCD11113155 | 358.478 | C22H30O4
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