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Filtered Search Results
Medchemexpress LLC Buflomedil (hydrochloride) | 35543-24-9 | 99.8% | 500 MG
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Buflomedil hydrochloride is a vasodilator agent and an orally active α1A-adrenoceptor antagonist. It is characterized by its Ki values of 4.06 μM for α1A-AR and 6.84 μM for α1B-AR. This compound is primarily used for the study of peripheral circulatory disorders.
- Vasodilator agent
- Orally active α1A-adrenoceptor antagonist
- Useful for studying peripheral circulatory disorders
- High purity of 99.8%
- Appears as a white to off-white solid
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Melevodopa hydrochloride | 1421-65-4 | 99.8% | 247.68 | 5 G
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Melevodopa hydrochloride is an effervescent Levodopa prodrug. Levodopa is an orally active metabolic precursor of the neurotransmitter dopamine and has anti-allodynic effects and potential for treating Parkinson's disease.
- Effervescent prodrug of Levodopa
- Metabolic precursor of dopamine
- Anti-allodynic effects
- Potential for Parkinson's disease treatment
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Medchemexpress LLC Octopamine hydrochloride | 770-05-8 | 99.9% | 1 G
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Octopamine hydrochloride is a biogenic monoamine structurally related to noradrenaline. It functions as a neurohormone, neuromodulator, and neurotransmitter in invertebrates, stimulating alpha2-adrenoceptors and increasing various metabolic processes. It mediates behaviors like learning and memory, regulates endocrine gland activity, and mobilizes lipids and carbohydrates through specific G protein-coupled receptors.
- Acts as a neurohormone, neuromodulator, and neurotransmitter
- Stimulates alpha2-adrenoceptors (ARs)
- Increases glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis, and portal perfusion pressure
- Regulates sensory input desensitization, arousal, and rhythmic behaviors
- Involved in complex behaviors like learning and memory
- Regulates endocrine gland activity
- Induces lipid and carbohydrate mobilization
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Medchemexpress LLC Ivabradine hydrochloride | 148849-67-6 | 99.7% | 1 ML
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Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker. It inhibits the cardiac pacemaker current (If), reducing heart rate dose-dependently without modifying blood pressure. This compound demonstrates anticonvulsant, anti-ischaemic, and anti-anginal activities.
- Potent and orally active HCN channel blocker
- Inhibits cardiac pacemaker current (If)
- Reduces heart rate dose-dependently
- Exhibits anticonvulsant activity
- Shows anti-ischaemic and anti-anginal effects
- Investigated in clinical trials for conditions such as heart failure and atrial fibrillation
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Medchemexpress LLC BI-4020 | 2664214-60-0 | 99.3% | 1 ML
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BI-4020 is a fourth-generation, orally active, and non-covalent EGFR tyrosine kinase inhibitor. It shows activity against various EGFR variants, including the triple mutant EGFR del19 T790M C797S, the double mutant EGFR del19 T790M, and primary mutant EGFR del19. It also exhibits activity against EGFR wt.
- Inhibits EGFR del19 T790M C797S variant with an IC50 of 0.2 nM
- Inhibits EGFR del19 T790M and EGFR del19 with an IC50 of 1 nM
- Exhibits high kinome selectivity
- Possesses good DMPK properties
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Medchemexpress LLC Vabicaserin hydrochloride | 887258-94-8 | 99.47% | 264.79 | 25 MG
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Vabicaserin hydrochloride is a 5-hydroxytryptamine 2C (5-HT2C) receptor-selective agonist with an EC50 of 8 nM, intended for research use only. It shows high selectivity over other serotonergic, noradrenergic, and dopaminergic receptors, with potent agonistic activity in stimulating 5-HT2C receptor-coupled calcium mobilization.
- 5-HT2C receptor-selective agonist
- Potent and full agonist (EC50, 8 nM)
- Stimulates 5-HT2C receptor-coupled calcium mobilization
- Exhibits 5-HT2A receptor antagonism
- Shows 5-HT2B antagonist or partial agonist activity
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eMolecules 29875-07-8 | 4-Methylbenzylmagnesium chloride, 0.5 M in 2-MeTHF | Synthonix - Stock | MFCD01319893 | 164.920 | C8H9ClMg | 0.000 | [Cl-].Cc1ccc(C[Mg+])cc1 | 100ml | 507877500
4-Methylbenzylmagnesium chloride, 0.5 M in 2-MeTHF | Synthonix - Stock | 29875-07-8 | MFCD01319893 | 164.920 | C8H9ClMg | 0.000 | [Cl-].Cc1ccc(C[Mg+])cc1 | 100ml | 507877500
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eMolecules 63488-08-4 | 2-iso-Propylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD06201611 | 223.396 | C9H11BrMg | 0.000 | [Br-].CC(C)c1ccccc1[Mg+] | 500ml | 437237407
2-iso-Propylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 63488-08-4 | MFCD06201611 | 223.396 | C9H11BrMg | 0.000 | [Br-].CC(C)c1ccccc1[Mg+] | 500ml | 437237407
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Medchemexpress LLC Amiodarone (hydrochloride) | 19774-82-4 | 99.9% | C25H30ClI2NO3 | 1 ML
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Amiodarone hydrochloride is a potent antiarrhythmic agent primarily used for severe cardiac arrhythmias. It belongs to Class III antiarrhythmics, characterized by its ability to prolong the action potential duration and refractory period in myocardial tissues. This product is provided as a 10 mM solution in DMSO, offering convenience for various research applications.
- Potent antiarrhythmic agent
- Prolongs action potential and refractory period
- Supplied as a 10 mM solution in DMSO
- Suitable for in vitro and in vivo research
- Recommended storage at -80°C for 6 months; -20°C for 1 month (sealed storage, away from moisture and light) when in solvent
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eMolecules 226570-68-9 | 4-Cyanobutylzinc bromide, 0.50 M in THF | Synthonix | MFCD01316996 | 227.410 | C5H8BrNZn | 0.000 | [Br-].[Zn+]CCCCC#N | 50ml | 532652712
4-Cyanobutylzinc bromide, 0.50 M in THF | Synthonix | 226570-68-9 | MFCD01316996 | 227.410 | C5H8BrNZn | 0.000 | [Br-].[Zn+]CCCCC#N | 50ml | 532652712
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eMolecules [4-Cyano-2-(trifluoromethyl)phenyl]zinc bromide, 0.5 M in THF | Synthonix |315.400 | C8H3BrF3NZn | 98.000 | [Br-].FC(F)(F)c1cc(ccc1[Zn+])C#N | 100ml | 818572016
[4-Cyano-2-(trifluoromethyl)phenyl]zinc bromide, 0.5 M in THF | Synthonix |315.400 | C8H3BrF3NZn | 98.000 | [Br-].FC(F)(F)c1cc(ccc1[Zn+])C#N | 100ml | 818572016
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eMolecules 87-13-8 | Diethyl 2-(ethoxymethylene)malonate | ChemScene | MFCD00009148 | 216.233 | C10H16O5 | 98.000 | CCOC=C(C(=O)OCC)C(=O)OCC | 25g | 791179235
Diethyl 2-(ethoxymethylene)malonate | ChemScene | 87-13-8 | MFCD00009148 | 216.233 | C10H16O5 | 98.000 | CCOC=C(C(=O)OCC)C(=O)OCC | 25g | 791179235
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eMolecules 7103-09-5 | 3-Butenylmagnesium bromide, 0.50 M in THF | Synthonix | MFCD00209554 | 159.309 | C4H7BrMg | 0.000 | [Br-].[Mg+]CCC=C | 25ml | 702445839
3-Butenylmagnesium bromide, 0.50 M in THF | Synthonix | 7103-09-5 | MFCD00209554 | 159.309 | C4H7BrMg | 0.000 | [Br-].[Mg+]CCC=C | 25ml | 702445839
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eMolecules 308795-93-9 | 4-Methyl-2-pyridylzinc bromide, 0.50 M in THF | Synthonix237.410 | C6H6BrNZn | 0.000 | [Br-].Cc1ccnc([Zn+])c1 | 100ml | 532652921
4-Methyl-2-pyridylzinc bromide, 0.50 M in THF | Synthonix | 308795-93-9237.410 | C6H6BrNZn | 0.000 | [Br-].Cc1ccnc([Zn+])c1 | 100ml | 532652921
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Medchemexpress LLC NNC-711 hydrochloride | 145645-62-1 | MFCD00153853 | 99.8% | 386.87 g/mol | C21H23ClN2O3 | 50 MG
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NNC-711 hydrochloride is a potent, selective inhibitor of the GABA transporter GAT-1 used as a research reagent in neuroscience. It exhibits anticonvulsant and analgesic effects in vivo and is commonly used to study GABA uptake and synaptic inhibition.
- Potent, selective inhibitor of GAT-1 with an IC50 of 0.04 μM (hGAT-1).
- Hydrochloride salt provided as a solid for laboratory use.
- Molecular weight 386.87 g/mol and formula C21H23ClN2O3.
- High purity (~99.8% as listed by the supplier).
- Supplied as a 50 MG research quantity suitable for in vitro and in vivo studies.
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