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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences 1-Naphthol BioXtra, >=99% | 90-15-3 | MFCD00003930 | 100G
1-Naphthol BioXtra, >=99% | Purity: >=99% | Mol Wt: 144.17 | 90-15-3 | MFCD00003930 | 100G
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Ambeed 2 2 2Trifluoro1 4methoxyphenyl
2,2,2-Trifluoro-1-(4-methoxyphenyl)ethanone, 711-38-6, 97%
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Chem-Impex International, Inc. 1-Amino-2-naphthol-4-sulfonic acid | MFCD00004019 | 25G
1-Amino-2-naphthol-4-sulfonic acid, MFCD00004019, 25G
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Chem-Impex International, Inc. a-Naphthol | 90-15-3 | MFCD00003930 | 250G
a-Naphthol, 90-15-3, MFCD00003930, 250G
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Medchemexpress LLC HY-B2156 100mg Medchemexpress, Menaquinone-4 CAS:863-61-6 Purity:>98%
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Medchemexpress, HY-B2156 100mg Menaquinone-4 CAS:863-61-6 Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Chem-Impex International, Inc. Arsenazo III | 1668-00-4 | MFCD00036695 | 1G
Arsenazo III, 1668-00-4, MFCD00036695, 1G
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Chem-Impex International, Inc. Vitamin K1 | 84-80-0 | MFCD00214063 | 5G
Vitamin K1, 84-80-0, MFCD00214063, 5G
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Sigma Aldrich Fine Chemicals Biosciences 1,3-Dihydroxynaphthalene >=99%, crystalline | 132-86-5 | MFCD00003965 | 1G
1,3-Dihydroxynaphthalene >=99%, crystalline | Purity: >=99% | Mol Wt: 160.17 | 132-86-5 | MFCD00003965 | 1G
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Sigma Aldrich Fine Chemicals Biosciences Salmeterol Xinafoate | 94749-08-3 | MFCD00897708 | 10mg
Salmeterol Xinafoate | Purity: 98% | Mol Wt: 603.75 | 94749-08-3 | MFCD00897708 | 10mg
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Apexbio Technology LLC Menadione, 10mM (in 1mL DMSO). Cas: 58-27-5 MFCD: MFCD00001681. precursor to vitamin K2
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Menadione (vitamin K3), used as a nutritional supplement, is an inhibitor of mitochondrial DNA polymerase γ (pol γ), with an IC 50 value of 6 µM. Pol γ is responsible for all aspects of mitochondrial DNA synthesis, including all replication, recombination of the mitochondrial genome, and repair of mitochondrial DNA damage. Other sizes are available. Please inqury us for quote.
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Ambeed AMBEED
5000894445 6-CHLORO-2-NAPHTHOIC ACI 250MG
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eMolecules 186354-48-3 | Ambeed | 13-Bis((R)-1-(naphthalen-1-yl)ethyl)-1H-imidazol-3-ium chloride | 100mg | 633660900 | A1473470 | 412.96 | C27H25ClN2
Medchem Express | SB-3CT | 5mg | 446261115 | HY-12354 | 292605-14-2 | MFCD09836266 | 306.390 | C15H14O3S2
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Medchemexpress LLC BI-2865 | 2937327-93-8 | C23H27N7O2S | 1 ML
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BI-2865 is a non-covalent pan-KRAS Inhibitor. It binds to wild-type and various mutant KRAS forms, including G12C, G12D, G12V, and G13D, inhibiting the proliferation of mutant KRAS expressing BaF3 cells. Characterized by a prolinol substituent and a pyrimidine linker, it forms specific interactions within the KRAS binding site. This product is for research use only.
- Binds to wild-type and various mutant KRAS forms
- Inhibits proliferation of mutant KRAS expressing BaF3 cells
- Features a prolinol substituent and a pyrimidine linker
- Demonstrates direct ionic interaction with E62
- Forms a water-mediated hydrogen bond network with R68 and Q61
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Medchemexpress LLC Phenformin (hydrochloride) | 834-28-6 | 99.6% | 241.72 | 1 G
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Phenformin hydrochloride is an anti-diabetic agent belonging to the biguanide class, known for its ability to activate AMPK activity. It stimulates the phosphorylation and activation of both AMPKalpha1 and AMPKalpha2 without altering LKB1 activity, and has been shown to increase AMPK activity and phosphorylation in isolated hearts, correlated with increased cytosolic [AMP].
- Activates AMPK activity
- Targets AMPK
- Inhibits mitochondrial complex I more potently than metformin
- Induces apoptosis in LKB1 deficient NSCLC cell lines
- Appears as a white to off-white solid
- High purity of 99.6%
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Medchemexpress LLC Fedratinib (hydrochloride hydrate) | 1374744-69-0 | 99.9% | 615.62 | 1 G
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Fedratinib hydrochloride hydrate is a potent, selective, ATP-competitive, and orally active inhibitor of JAK2. It exhibits an IC50 of 3 nM for both JAK2 and JAK2V617F kinase and demonstrates significant selectivity over JAK1 (35-fold) and JAK3 (334-fold). This compound has been shown to induce apoptosis in cancer cells and is considered to have potential for research in myeloproliferative disorders.
- Potent, selective, ATP-competitive, and orally active JAK2 inhibitor.
- Targets both JAK2 and JAK2V617F kinase effectively at 3 nM IC50.
- Exhibits high selectivity against JAK1 (35-fold) and JAK3 (334-fold).
- Induces apoptosis in cancer cells.
- Shows promise for research in myeloproliferative disorders.
- Inhibits proliferation of cell lines carrying the JAK2V617F mutation.
- Reduces STAT5 phosphorylation.
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