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Medchemexpress LLC Tetrahydrofolic acid | 135-16-0 | C19H23N7O6 | 100 MG
Supplier: Medchemexpress LLC HY14520100MG
Tetrahydrofolic acid is the biologically active vitamin B9 folate derivative. It acts as a donor of one-carbon groups for amino acids, nucleic acids, and lipids, and serves as an acceptor of free formaldehyde, producing 5,10-methylenetetrahydrofolate-Tetrahydrofolic acid.
- Functions as an endogenous metabolite
- Induces cytotoxicity in Adh5- and Fanconi anemia (FA)-deficient cells
- Promotes FANCD2 and ser139-H2AX focus formation in Adh5-/- cells
- Activates the DNA damage response
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