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Filtered Search Results
Medchemexpress LLC 4-Chloro-1-naphthol | 604-44-4 | 178.62 | 500 MG
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4-Chloronaphthalen-1-ol is a substrate of horseradish peroxidase. It can be used to visualize protein bands in western blotting and immunohistochemical staining.
- Used to visualize protein bands in western blotting.
- Used in immunohistochemical staining.
- Substrate to stain cryosections black by indirect immunoperoxidase staining.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 36321-90-1 | 2-Methoxy-1-naphthylmagnesium bromide, 0.25 M in THF | Synthonix - Stock261.401 | C11H9BrMgO | 0.000 | [Br-].COc1ccc2ccccc2c1[Mg+] | 50ml | 437237304
2-Methoxy-1-naphthylmagnesium bromide, 0.25 M in THF | Synthonix - Stock | 36321-90-1261.401 | C11H9BrMgO | 0.000 | [Br-].COc1ccc2ccccc2c1[Mg+] | 50ml | 437237304
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eMolecules 935433-88-8 | (5-chloropyridin-2-yl)zinc bromide, 0.25 M in THF | Synthonix257.820 | C5H3BrClNZn | 0.000 | [Br-].Clc1ccc([Zn+])nc1 | 100ml | 532652655
(5-chloropyridin-2-yl)zinc bromide, 0.25 M in THF | Synthonix | 935433-88-8257.820 | C5H3BrClNZn | 0.000 | [Br-].Clc1ccc([Zn+])nc1 | 100ml | 532652655
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Medchemexpress LLC Migalastat (hydrochloride) | 75172-81-5 | 99.7% | 199.63 | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Migalastat hydrochloride (GR181413A) is an orally active α-galactosidase A molecular chaperone. It binds to the active site of unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. Upon dissociation in the acidic environment, Migalastat enables these mutant enzymes to regain biological activity. It exhibits an IC50 and Ki value of 0.04 μM for human α-Gal A.
- Orally active α-galactosidase A molecular chaperone
- IC50 and Ki of 0.04 μM for human α-Gal A
- Facilitates transport and restores activity of mutant α-galactosidase A enzymes
- Reduces Gb3 accumulation and lysosome volume in vitro
- Increases α-Gal A activity in heart, kidney, spleen, and liver in transgenic mice
- Reduces lyso-Gb3 levels in kidney, heart, and skin in transgenic mice
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eMolecules 119272-62-7 | 4-Benzyloxybutylmagnesium bromide, 0.50 M in THF | Synthonix267.449 | C11H15BrMgO | 0.000 | [Br-].[Mg+]CCCCOCc1ccccc1 | 25ml | 804019709
4-Benzyloxybutylmagnesium bromide, 0.50 M in THF | Synthonix | 119272-62-7267.449 | C11H15BrMgO | 0.000 | [Br-].[Mg+]CCCCOCc1ccccc1 | 25ml | 804019709
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Medchemexpress LLC SOCE inhibitor 1 | 2169316-15-6 | 99.7% | 513.47 | 10 MG
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SOCE inhibitor 1 | 2169316-15-6 | 99.7% | 513.47 | 10 MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules (3-Chloro-5-cyanophenyl)zinc bromide, 0.5 M in THF | Synthonix |281.840 | C7H3BrClNZn | 0.000 | [Br-].Clc1cc([Zn+])cc(c1)C#N | 50ml | 812584954
(3-Chloro-5-cyanophenyl)zinc bromide, 0.5 M in THF | Synthonix |281.840 | C7H3BrClNZn | 0.000 | [Br-].Clc1cc([Zn+])cc(c1)C#N | 50ml | 812584954
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eMolecules 135579-85-0 | 3-Cyanopropylzinc bromide, 0.50 M in THF | Synthonix | MFCD00671975 | 213.380 | C4H6BrNZn | 97.000 | [Br-].[Zn+]CCCC#N | 100ml | 532652697
3-Cyanopropylzinc bromide, 0.50 M in THF | Synthonix | 135579-85-0 | MFCD00671975 | 213.380 | C4H6BrNZn | 97.000 | [Br-].[Zn+]CCCC#N | 100ml | 532652697
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eMolecules Synthonix 4-Chlorobutylzinc bromide 0.50 M in THF 25ml 627353562 C73229 155589-48-3 MFCD01316995 236.840 C4H8BrClZn
Synthonix 4-Chlorobutylzinc bromide 0.50 M in THF 25ml 627353562 C73229 155589-48-3 MFCD01316995 236.840 C4H8BrClZn
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Medchemexpress LLC Acoramidis hydrochloride | 2242751-53-5 | 98.5% | 328.77 | 1 ML
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Acoramidis (AG10) hydrochloride is an orally active and selective kinetic stabilizer of WT and V122I-TTR (transthyretin). It is used in the study for transthyretin amyloidosis. It is for research use only and not sold to patients.
- Orally active and selective kinetic stabilizer of WT and V122I-TTR (transthyretin).
- Stimulates mitochondrial QO2 in a concentration-dependent manner between 10 and 100 μM.
- Has very minimal inhibition of two common off-targets in drug discovery, the potassium ion channel hERG (IC50 > 100 μM) and a number of cytochrome P450 isozymes (IC50 > 50 μM), indicating low toxicity.
- More effective than tafamidis in stabilizing TTR in human serum.
- In animal models, it showed no signs of pathologic processes in liver, kidney, heart, spleen, thymus, and lung at a dosage of 50 mg/kg/d (oral gavage for 28 days).
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eMolecules 224311-55-1 | (2-Biphenyl)di-1-adamantylphosphine | ChemScene454.638 | C32H39P | 97.000 | C1C2CC3CC1CC(C2)(C3)P(c1ccccc1-c1ccccc1)C12CC3CC(CC(C3)C1)C2 | 250mg | 572192941
(2-Biphenyl)di-1-adamantylphosphine | ChemScene | 224311-55-1454.638 | C32H39P | 97.000 | C1C2CC3CC1CC(C2)(C3)P(c1ccccc1-c1ccccc1)C12CC3CC(CC(C3)C1)C2 | 250mg | 572192941
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Medchemexpress LLC BI-27 SUPPLEMENT 50 50ML
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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BI-27 SUPPLEMENT 50 50ML
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eMolecules 119272-62-7 | 4-Benzyloxybutylmagnesium bromide, 0.50 M in THF | Synthonix267.449 | C11H15BrMgO | 0.000 | [Br-].[Mg+]CCCCOCc1ccccc1 | 50ml | 804019710
4-Benzyloxybutylmagnesium bromide, 0.50 M in THF | Synthonix | 119272-62-7267.449 | C11H15BrMgO | 0.000 | [Br-].[Mg+]CCCCOCc1ccccc1 | 50ml | 804019710
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Medchemexpress LLC ANCITABINE HYDROCHL 1G
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ANCITABINE HYDROCHL 1G
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eMolecules 352530-44-0 | 4-Bromo-2-fluorophenylzinc iodide, 0.50 M in THF | Synthonix366.280 | C6H3BrFIZn | 0.000 | [I-].Fc1cc(Br)ccc1[Zn+] | 50ml | 532652624
4-Bromo-2-fluorophenylzinc iodide, 0.50 M in THF | Synthonix | 352530-44-0366.280 | C6H3BrFIZn | 0.000 | [I-].Fc1cc(Br)ccc1[Zn+] | 50ml | 532652624
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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