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Filtered Search Results
Medchemexpress LLC Siglec-10 Human Bi 20ug
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Siglec-10 protein is thought to be a putative adhesion molecule that mediates sialic acid-dependent cell binding preferentially selecting -2 3- or -2 6-linked sialic acid Its sialic acid recognition site may be masked by cis interactions Siglec-10 Protein Human (Biotinylated HEK293 Fc-Avi) is the recombinant human-derived Siglec-10 protein expressed by HEK293 with C-Avi C-hFc labeled tag
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Medchemexpress LLC BI-2493 | 2937344-16-4 | C24H27N7OS | 50 MG
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BI-2493 is a structural analogue of BI-2865 and a highly selective and orally active pan-KRAS inhibitor. It is designed to attenuate tumor growth and is primarily used for cancer diseases research.
- Highly selective and orally active pan-KRAS inhibitor
- Attenuates tumor growth
- Used for cancer diseases research
- Inhibits proliferation of KRAS mutant cancer cell lines in a concentration-dependent manner
- Exhibits tumor-suppressive activity in xenograft mouse models
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Cayman Chemical Naphthol AS-E Phosphate 25mg
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An inhibitor of the protein-protein interaction between CREB and KIX domains; disrupts binding between CREB and the KIX domain of CBP (Ki = 50 µM); inhibits binding of Myb to the KIX domains of p300 and CBP (IC50s = 30 and 43 µM, respectively); inhibits CREB-dependent transcription in HEK293T cells (Ki = 10 µM); decreases the expression of Myb target genes and induces differentiation in HL-60, U937, and NB4 myeloid leukemia cells at 5 µM; inhibits proliferation of NCI-H1734 lung adenocarcinoma cells (IC50 = 6.89 µM)
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AdipoGen n-Dodecyl-beta-D-maltoside
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Chemical. CAS 69227-93-6. Formula C24H46O11. MW 510.6. Water-soluble non-ionic detergent with a hydrophilic maltose head and a hydrophobic long chain alkyl tail. It is considered a gentle detergent that is more efficient than other detergents. For functional solubilization and purification of membrane proteins. It helps to retain the native conformation and activity of membrane-associated proteins and facilitates the reforming of these proteins after denaturation. For the stabilization and activation of enzymes. The critical micelle concentration of DDM is approx. 0.18 mM in water, decreases in the presence of sodium chloride or sucrose and increases in urea.
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Apexbio Technology LLC Naphthol AS-MX phosphate 1596-56-1 50mg
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Naphthol AS-MX phosphate (CAS 1596-56-1) is a small molecule inhibitor that disrupts the interaction between cAMP response element-binding protein (CREB) and CREB-binding protein (CBP) key components of a transcription factor complex In lung cancer cells it demonstrates antiproliferative effects as evidenced by an IC50 of 3 701 mol/L and inhibits both colony formation and anchorage-independent growth Naphthol AS-MX phosphate is utilized in studies investigating KRAS-mutant lung cancers particularly in the context of chemoresistance and poor prognosis
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Medchemexpress LLC 1-[(3,5-dichlorophenyl)sulfonyl]-N-[(4-fluorophenyl)methyl]-4-piperidinecarboxamide | 2227549-00-8 | 99.3% | 445.34 g/mol | C19H19Cl2FN2O3S | 10MM 1ML
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BI01383298 is a small-molecule chemical probe that potently and selectively inhibits the human sodium-citrate co-transporter SLC13A5 (NaCT). It is supplied as a 10 mM solution in DMSO for in vitro research and shows low-nanomolar potency (IC50 ≈56 nM in HEK cells overexpressing SLC13A5; 24 nM in HepG2 cells) with >1,000-fold selectivity versus related family members. Typical supplied purity is ~99.3%, and the molecular formula is C19H19Cl2FN2O3S (MW ≈445 g/mol).
- Potent SLC13A5 inhibition at low nanomolar concentrations.
- High selectivity versus related transporters.
- Supplied as a 10 mM solution in DMSO, 1 mL.
- High purity suitable for biochemical assays.
- Intended for in vitro research use; not recommended for mouse models.
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eMolecules 473694-19-8 | 4-Chloro-3-fluorophenylzinc bromide, 0.50 M in THF | Synthonix274.820 | C6H3BrClFZn | 0.000 | [Br-].Fc1cc([Zn+])ccc1Cl | 50ml | 703157768
4-Chloro-3-fluorophenylzinc bromide, 0.50 M in THF | Synthonix | 473694-19-8274.820 | C6H3BrClFZn | 0.000 | [Br-].Fc1cc([Zn+])ccc1Cl | 50ml | 703157768
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eMolecules 205319-10-4 | Dichloro[9,9-dimethyl-4,5-bis(diphenylphosphino)xanthene]palladium(II) | Combi-Blocks, Inc. | MFCD14155707 | 755.950 | C39H32Cl2OP2Pd | 97.000 | [Cl-].[Cl-].[Pd++].CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(cccc12)P(c1ccccc1)c1ccccc1 | 5g | 586075590
Dichloro[9,9-dimethyl-4,5-bis(diphenylphosphino)xanthene]palladium(II) | Combi-Blocks, Inc. | 205319-10-4 | MFCD14155707 | 755.950 | C39H32Cl2OP2Pd | 97.000 | [Cl-].[Cl-].[Pd++].CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(cccc12)P(c1ccccc1)c1ccccc1 | 5g | 586075590
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Medchemexpress LLC Celgosivir hydrochloride | 141117-12-6 | 98.0% | 295.76 | 100 MG
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Celgosivir hydrochloride | 141117-12-6 | 98.0% | 295.76 | 100 MG
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eMolecules 738580-35-3 | 2-Biphenylzinc iodide, 0.50 M in THF | Synthonix | MFCD07698713 | 345.490 | C12H9IZn | 0.000 | [I-].[Zn+]c1ccccc1-c1ccccc1 | 25ml | 627353495
2-Biphenylzinc iodide, 0.50 M in THF | Synthonix | 738580-35-3 | MFCD07698713 | 345.490 | C12H9IZn | 0.000 | [I-].[Zn+]c1ccccc1-c1ccccc1 | 25ml | 627353495
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eMolecules 88303-25-7 | Tetradecylmagnesium bromide, 0.50 M in THF | Synthonix301.595 | C14H29BrMg | 0.000 | [Br-].CCCCCCCCCCCCCC[Mg+] | 50ml | 702445997
Tetradecylmagnesium bromide, 0.50 M in THF | Synthonix | 88303-25-7301.595 | C14H29BrMg | 0.000 | [Br-].CCCCCCCCCCCCCC[Mg+] | 50ml | 702445997
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eMolecules 1372548-45-2 | Tetrahydropyran-4-ylzinc bromide, 0.50 M in THF | Synthonix230.410 | C5H9BrOZn | 95.000 | [Br-].[Zn+]C1CCOCC1 | 100ml | 532653007
Tetrahydropyran-4-ylzinc bromide, 0.50 M in THF | Synthonix | 1372548-45-2230.410 | C5H9BrOZn | 95.000 | [Br-].[Zn+]C1CCOCC1 | 100ml | 532653007
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AdipoGen 3 4-Dihydroxy-L-phenylalanine
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Chemical. CAS 59-92-7. Formula C9H11NO4. MW 197.19. Synthetic. Metabolic precursor of the neurotransmitters dopamine, norepinephrine noradrenaline, and epinephrine adrenaline, which are collectively known as catecholamines. This amino acid is produced from L-tyrosine by tyrosine hydroxylase and metabolized by catechol-O-methyl transferase COMT. L-DOPA is capable of crossing the blood brain barrier where it is converted to dopamine. Formulations containing L-DOPA have been used to increase dopamine concentrations in the brain as a treatment for Parkinson’s disease and stroke recovery. Mediates neurotrophic factor release by the brain and CNS. Used for the treatment of Parkinson’s disease and dopamine-responsive dystonia. In addition it is used, as a cell adhesion molecule in serum-free cultures of anchorage-dependent mammalian cells, to prevent surfaces from fouling by bonding antifouling polymers to a susceptible substrate or to stain melanocytes.
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eMolecules Synthonix 5-Bromo-2-thienylzinc bromide 0.50 M in THF 25ml 627353510 B73258 151073-94-8 MFCD00671986 307.310 C4H2Br2SZn
Synthonix 5-Bromo-2-thienylzinc bromide 0.50 M in THF 25ml 627353510 B73258 151073-94-8 MFCD00671986 307.310 C4H2Br2SZn
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eMolecules 312693-45-1 | 3-Methyl-2-thienylzinc bromide, 0.50 M in THF | Synthonix242.440 | C5H5BrSZn | 0.000 | [Br-].Cc1ccsc1[Zn+] | 100ml | 532652909
3-Methyl-2-thienylzinc bromide, 0.50 M in THF | Synthonix | 312693-45-1242.440 | C5H5BrSZn | 0.000 | [Br-].Cc1ccsc1[Zn+] | 100ml | 532652909
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