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Filtered Search Results
eMolecules 220565-63-9 | 3-Pyridylzinc bromide, 0.50 M in THF | Synthonix | MFCD11915899 | 223.380 | C5H4BrNZn | 0.000 | [Br-].[Zn+]c1cccnc1 | 100ml | 532652951
3-Pyridylzinc bromide, 0.50 M in THF | Synthonix | 220565-63-9 | MFCD11915899 | 223.380 | C5H4BrNZn | 0.000 | [Br-].[Zn+]c1cccnc1 | 100ml | 532652951
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TARGETMOL CHEMICALS INC BI-3812 5MG
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Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BI-3812 is an inhibitor of BCL6. Which inhibiting the BTB domain of BCL6 (IC50 3 nM). BI-3812 also has antitumor activity. purity: 99%
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Medchemexpress LLC Mocravimod hydrochloride | 509088-69-1 | 99.99% | 480.45 | 25 MG
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Mocravimod hydrochloride is an orally active sphingosine-1-phosphate receptor (S1PR) modulator that blocks the signal T cells need to egress from lymph nodes and other lymphoid organs. It preferentially binds to S1PR1 and can be used for the study of acute myelogenous leukemia, diabetes, and Myocardial Ischemia-Reperfusion Injury (MIRI).
- Blocks T cell egress from lymph nodes
- Preferentially binds to S1PR1
- Lowers reactive oxygen species (ROS) concentration
- Prevents mitochondrial permeability transition pore opening
- Boosts mitochondrial membrane potential (MMP)
- Increases phosphorylation of AKT, EKR, GSK-3β, JAK2, and STAT3
- Retains T cell effector function
- Suitable for studying acute myelogenous leukemia, diabetes, and Myocardial Ischemia-Reperfusion Injury (MIRI)
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eMolecules 1227833-81-9 | 4-Methyl-3-pyridylzinc bromide, 0.50 M in THF | Synthonix237.410 | C6H6BrNZn | 0.000 | [Br-].Cc1ccncc1[Zn+] | 25ml | 627353705
4-Methyl-3-pyridylzinc bromide, 0.50 M in THF | Synthonix | 1227833-81-9237.410 | C6H6BrNZn | 0.000 | [Br-].Cc1ccncc1[Zn+] | 25ml | 627353705
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eMolecules 131379-17-4 | 2-Cyanophenylzinc bromide, 0.50 M in THF | Synthonix | MFCD00671983 | 247.400 | C7H4BrNZn | 0.000 | [Br-].[Zn+]c1ccccc1C#N | 50ml | 532652680
2-Cyanophenylzinc bromide, 0.50 M in THF | Synthonix | 131379-17-4 | MFCD00671983 | 247.400 | C7H4BrNZn | 0.000 | [Br-].[Zn+]c1ccccc1C#N | 50ml | 532652680
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eMolecules 103068-18-4 | 3-Biphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock257.413 | C12H9BrMg | 0.000 | [Br-].[Mg+]c1cccc(c1)-c1ccccc1 | 500ml | 437236967
3-Biphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 103068-18-4257.413 | C12H9BrMg | 0.000 | [Br-].[Mg+]c1cccc(c1)-c1ccccc1 | 500ml | 437236967
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eMolecules 254454-47-2 | 4-Methoxyphenylzinc iodide, 0.50 M in THF | Synthonix | MFCD01311444 | 299.420 | C7H7IOZn | 0.000 | [I-].COc1ccc([Zn+])cc1 | 25ml | 627353703
4-Methoxyphenylzinc iodide, 0.50 M in THF | Synthonix | 254454-47-2 | MFCD01311444 | 299.420 | C7H7IOZn | 0.000 | [I-].COc1ccc([Zn+])cc1 | 25ml | 627353703
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eMolecules 1204580-76-6 | 5-Tributylstannyl-2-trifluoromethylpyridine | Synthonix - Stock | MFCD11109387 | 436.150 | C18H30F3NSn | 96.000 | CCCC[Sn](CCCC)(CCCC)c1ccc(nc1)C(F)(F)F | 5g | 525924052
5-Tributylstannyl-2-trifluoromethylpyridine | Synthonix - Stock | 1204580-76-6 | MFCD11109387 | 436.150 | C18H30F3NSn | 96.000 | CCCC[Sn](CCCC)(CCCC)c1ccc(nc1)C(F)(F)F | 5g | 525924052
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eMolecules 278605-08-6 | 5-Chloropentylmagnesium bromide, 0.50 M in THF | Synthonix209.790 | C5H10BrClMg | 0.000 | [Br-].[Mg+]CCCCCCl | 50ml | 702445867
5-Chloropentylmagnesium bromide, 0.50 M in THF | Synthonix | 278605-08-6209.790 | C5H10BrClMg | 0.000 | [Br-].[Mg+]CCCCCCl | 50ml | 702445867
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eMolecules (4-Cyano-3,5-difluorophenyl)zinc bromide, 0.5 M in THF | Synthonix |283.380 | C7H2BrF2NZn | 0.000 | [Br-].Fc1cc([Zn+])cc(F)c1C#N | 100ml | 812584958
(4-Cyano-3,5-difluorophenyl)zinc bromide, 0.5 M in THF | Synthonix |283.380 | C7H2BrF2NZn | 0.000 | [Br-].Fc1cc([Zn+])cc(F)c1C#N | 100ml | 812584958
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Medchemexpress LLC BI-4020 | 2664214-60-0 | 98.82% | 50 MG
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BI-4020 is a fourth-generation, orally active, and non-covalent EGFR tyrosine kinase inhibitor. It exhibits high kinome selectivity and favorable DMPK properties. This compound is stable under recommended storage conditions.
- Inhibits the triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM in BaF3 cell lines).
- Inhibits the double mutant EGFR del19 T790M and primary mutant EGFR del19 (IC50=1 nM).
- Shows activity against EGFR wt (IC50=190 nM).
- For research use only by suitably qualified experienced scientists.
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Medchemexpress LLC Loperamide hydrochloride | 34552-83-5 | 99.8% | 1 ML
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Loperamide hydrochloride (R-18553 hydrochloride) is an opioid receptor agonist and a selective, competitive human intestinal carboxylesterases (hiCE) inhibitor. It is primarily recognized for its anti-diarrheal effects and is extensively used in research settings to study its impact on various biological pathways.
- Induces hallmarks of ER stress and autophagy in GBM cells and MEFs.
- Decreases LC3B and GABARAP lipidation levels in ATF4 KO cells compared to WT cells.
- Used in cell autophagy assays.
- Store at 4°C, sealed and away from moisture.
- For solutions, store at -80°C for up to 6 months or -20°C for 1 month, sealed and away from moisture.
- Shipped at room temperature for durations less than 2 weeks.
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Medchemexpress LLC Ivabradine (hydrochloride) | 148849-67-6 | 99.7% | 100 MG
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Ivabradine (hydrochloride) is a potent and orally active blocker of HCN (hyperpolarization-activated cyclic nucleotide-gated) channels. It inhibits the cardiac pacemaker current (If) and is known to reduce heart rate in a dose-dependent manner without affecting blood pressure. This compound exhibits anticonvulsant, anti-ischaemic, and anti-anginal activities, making it suitable for various research applications.
- Potent and orally active HCN channel blocker
- Inhibits cardiac pacemaker current (If)
- Reduces heart rate dose-dependently without affecting blood pressure
- Exhibits anticonvulsant activity
- Exhibits anti-ischaemic activity
- Exhibits anti-anginal activity
- Intended for research and analytical applications
- Purity of 99.7%
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Medchemexpress LLC Forodesine hydrochloride | 284490-13-7 | 98.4% | 302.71 | 25 MG
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Forodesine hydrochloride is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. It is a potent human lymphocyte proliferation inhibitor and can induce apoptosis in leukemic cells by increasing dGTP levels.
- Potent and orally active purine nucleoside phosphorylase (PNP) inhibitor.
- Inhibits human lymphocyte proliferation.
- Induces apoptosis in leukemic cells.
- Excellent oral bioavailability in mice.
- Effective in prolonging life span in mouse models.
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Medchemexpress LLC Forodesine hydrochloride | 284490-13-7 | 99.9% | 302.71 | 1 ML
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Forodesine hydrochloride is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor. It acts as a potent human lymphocyte proliferation inhibitor and can induce apoptosis in leukemic cells by increasing dGTP levels. It has excellent oral bioavailability in mice.
- Highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor
- Potent human lymphocyte proliferation inhibitor
- Induces apoptosis in leukemic cells
- Excellent oral bioavailability in mice
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