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Polycyclic aromatic hydrocarbon compounds that consist of ten carbon atoms and eight hydrogen atoms fused into two benzene rings; it is the simplest polycyclic aromatic hydrocarbon.
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BI-2536 is a potent Plk1 inhibitor with IC50 of 0 83 nM in a cell-free assay BI-2536 inhibits Bromodomain 4 (BRD4) with Kd of 37 nM and potently suppresses c-Myc expression BI-2536 induces apoptosis and attenuates autophagy Phase 2
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