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Tetralins

Bicyclic hydrocarbon compounds that consist of ten carbon atoms and twelve hydrogen atoms linearly fused into two rings, where one ring is a benzene.
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5-Methoxy-2-tetralone 95.0+%, TCI America™

CAS: 32940-15-1 Molecular Formula: C11H12O2 Molecular Weight (g/mol): 176.22 MDL Number: MFCD00064958 InChI Key: MDAIAXRTLTVEOU-UHFFFAOYSA-N Synonym: 3,4-Dihydro-5-methoxy-2(1H)-naphthalenone PubChem CID: 259194 IUPAC Name: 5-methoxy-1,2,3,4-tetrahydronaphthalen-2-one SMILES: COC1=CC=CC2=C1CCC(=O)C2

PubChem CID 259194
CAS 32940-15-1
Molecular Weight (g/mol) 176.22
MDL Number MFCD00064958
SMILES COC1=CC=CC2=C1CCC(=O)C2
Synonym 3,4-Dihydro-5-methoxy-2(1H)-naphthalenone
IUPAC Name 5-methoxy-1,2,3,4-tetrahydronaphthalen-2-one
InChI Key MDAIAXRTLTVEOU-UHFFFAOYSA-N
Molecular Formula C11H12O2
2

Apexbio Technology LLC A-317491(Synonyms: A317491, A-317491 sodium salt hydrate, P2X3 receptor antagonist A-317491, A 317491), 5mg, CAS: 475205-49-3.
SDP

A-317491 (CAS 475205-49-3) is a selective high-affinity antagonist targeting the P2X3 and heteromeric P2X2/3 receptors ligand-gated ion channels responsive to ATP primarily located on sensory neurons involved in pain signaling It demonstrates potent inhibition with reported Ki values of 9 nM (P2X2/3) and 22 nM (P2X3) In rat dorsal root ganglion neurons A-317491 suppresses receptor-mediated currents (IC50 15 nM) in a dose-dependent manner In animal models intrathecal or peripheral administration attenuates hyperalgesia associated with inflammation and neuropathic pain underscoring its utility in pain research

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