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Organic compounds that consist of a carboxylic acid with a vinyl functional group substitution; vinyl functional groups are a carbon - carbon double bond. Includes compounds that are derived from acrylic acids.
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Mepyramine maleate (CAS 59-33-6) is a selective antagonist of the histamine H1 receptor exhibiting dissociation constants of 0 8 nM for H1 5200 nM for H2 and over 3000 nM for H3 receptors By blocking H1 receptor-mediated signaling it modulates pathways involved in allergic responses Mepyramine maleate is commonly utilized in experimental models of allergic diseases to investigate histamine-related mechanisms and to delineate the role of H1 receptor activity in immunological and inflammatory processes
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