Hydroxy acids and derivatives
Apexbio Technology LLC Varenicline Tartrate 375815-87-5 5mg
Varenicline tartrate (CAS 375815-87-5) is an orally bioavailable small molecule that acts as a partial agonist with high selectivity for 4 2 nicotinic acetylcholine receptors (Ki 0 06 nM) while displaying significantly lower affinity for 3 4 7 and 1 subtypes (Ki 240 322 and 3540 nM respectively) In vitro studies demonstrate that varenicline tartrate reduces nicotine-induced dopamine release and in vivo research shows decreased nicotine self-administration This compound is widely utilized in neuropharmacological investigations of nicotinic receptor modulation and nicotine dependence mechanisms
Apexbio Technology LLC Varenicline Tartrate 375815-87-5 25mg
Varenicline tartrate (CAS 375815-87-5) is an orally bioavailable small molecule that acts as a partial agonist with high selectivity for 4 2 nicotinic acetylcholine receptors (Ki 0 06 nM) while displaying significantly lower affinity for 3 4 7 and 1 subtypes (Ki 240 322 and 3540 nM respectively) In vitro studies demonstrate that varenicline tartrate reduces nicotine-induced dopamine release and in vivo research shows decreased nicotine self-administration This compound is widely utilized in neuropharmacological investigations of nicotinic receptor modulation and nicotine dependence mechanisms