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Apexbio Technology LLC Varenicline Tartrate 375815-87-5 5mg
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Catalog No. 5000094017
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Varenicline tartrate (CAS 375815-87-5) is an orally bioavailable small molecule that acts as a partial agonist with high selectivity for 4 2 nicotinic acetylcholine receptors (Ki 0 06 nM) while displaying significantly lower affinity for 3 4 7 and 1 subtypes (Ki 240 322 and 3540 nM respectively) In vitro studies demonstrate that varenicline tartrate reduces nicotine-induced dopamine release and in vivo research shows decreased nicotine self-administration This compound is widely utilized in neuropharmacological investigations of nicotinic receptor modulation and nicotine dependence mechanisms

Catalog No. 50-000-94017 Supplier Apexbio Technology LLC Supplier No. A53915
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Varenicline tartrate (CAS 375815-87-5) is an orally bioavailable small molecule that acts as a partial agonist with high selectivity for 4 2 nicotinic acetylcholine receptors (Ki 0 06 nM) while displaying significantly lower affinity for 3 4 7 and 1 subtypes (Ki 240 322 and 3540 nM respectively) In vitro studies demonstrate that varenicline tartrate reduces nicotine-induced dopamine release and in vivo research shows decreased nicotine self-administration This compound is widely utilized in neuropharmacological investigations of nicotinic receptor modulation and nicotine dependence mechanisms

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