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Organic compounds that consist of sulfuric acid with organic functional group substitutions; includes compounds that are derived from organic sulfuric acids.
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This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
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Colistin sulfate is a polypeptide antibiotic which inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria.
Polypeptide antibiotic
Inhibits gram-negative bacteria
Purity of >98%
Powder storage at -20°C for 3 years or 4°C for 2 years
In solvent storage at -80°C for 6 months or -20°C for 1 month
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Colistin Sulfate (1264-72-8) is a cyclic antimicrobial peptide targeting the outer membrane of Gram-negative bacteria It is designed to interact electrostatically with negatively charged lipopolysaccharides thereby disrupting membrane integrity and permeability Colistin Sulfate exerts its biological activity primarily through disruption of the bacterial outer membrane In bacterial inhibition assays Colistin Sulfate demonstrates inhibitory activity with IC50 values typically ranging from 0 5 5 g/mL depending on the bacterial strain and experimental conditions Based on these pharmacological properties Colistin Sulfate holds research potential in antimicrobial applications particularly against multidrug-resistant Gram-negative organisms and as a selective agent in bacterial cell culture protocols
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