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Organic compounds that consist of sulfuric acid with organic functional group substitutions; includes compounds that are derived from organic sulfuric acids.
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Framycetin sulfate is an aminoglycoside antibiotic that acts as a potent inhibitor of RNase P cleavage activity. It competes for specific divalent metal ion binding sites in RNase P RNA and also inhibits hammerhead ribozyme. This compound is a 5″-azido neomycin B precursor and binds to the Drosha site in miR-525. It is used in the treatment of hepatic encephalopathy and infections caused by enteropathogenic E. coli.
Potent RNase P cleavage activity inhibitor
Inhibits hammerhead ribozyme
Binds to the Drosha site in miR-525
Effective against hepatic encephalopathy and enteropathogenic E. coli infections
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