Azepines
Cayman Chemical CondurItol B epoxIde 50mg
An irreversible inhibitor of GBA (IC50 = 9 μM); does not inhibit non-lysosomal glucosylceramidase or cytosolic β-glucosidase
Medchemexpress LLC 1-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester | 286961-14-6 | 99.8% | 309.21 | 50 G
1-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is for research use only and not sold to patients.
- Biochemical reagent for research applications.
- Can be utilized as a biological material or organic compound.
- Supports various life science related research.
- Intended solely for research purposes.
- Not available for patient use.
Medchemexpress LLC Eslicarbazepine acetate | 236395-14-5 | 99.9% | 500 MG
Eslicarbazepine acetate (BIA 2-093) is an antiepileptic agent that functions as a dual inhibitor of β-Secretase and voltage-gated sodium channels. It is a prodrug that is converted to eslicarbazepine, an active metabolite of oxcarbazepine, sharing an identical mechanism of action. This compound may offer improved tolerability compared to oxcarbazepine by not producing as high peak levels of (S)-(+)-licarbazepine immediately after dosing.
- Functions as an antiepileptic agent
- Dual inhibitor of β-Secretase and voltage-gated sodium channels
- Prodrug activated to eslicarbazepine
- Mechanism of action identical to oxcarbazepine
- May improve tolerability over oxcarbazepine
- Targets beta-secretase and sodium channel pathways
- Involved in neuronal signaling and membrane transporter/ion channel pathways
eMolecules 91774-53-7 | 1H-Azepin-4-Ol, Hexahydro-4-Methyl Hydrochloride | 250mg
WuXi AppTec | 1H-Azepin-4-Ol, Hexahydro-4-Methyl Hydrochloride | 250mg | 583179080 | LN00004472 | 91774-53-7 | 165.660 | C7H16ClNO
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Medchemexpress LLC Carbamazepine-(Ph)d8 | 1538624-35-9 | 98.7% | 1 MG
Carbamazepine-(Ph)d8 is a deuterium-labeled compound intended for research use only. It can be used as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration, the incorporation of stable heavy isotopes into drug molecules, has gained attention for its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cayman Chemical CarbamazepIn 5g
A sodium channel inhibitor; preferentially inhibits inactivated Nav1.7 and Nav1.3 channels (IC50s = 406 and 900 µM, respectively) over resting (closed) Nav1.7 and Nav1.3 channels in whole-cell patch-clamp assays using HEK293 cells (IC50s = 1,584 and 2,464 µM, respectively); inhibits sodium currents in a rat sciatic nerve patch-clamp assay ex vivo at 100 µM; reduces dopamine levels in the striatum and hippocampus, as well as L-DOPA levels in the striatum, in rats at 100 mg/kg; reduces amphetamine-induced hyperactivity in mice at 0.5% w/w in the diet; reduces immobility time in the forced swim test in mice at 0.75% w/w in the diet
Selleck Chemical LLC Carbamazepine-50mg
Carbamazepine (Carbatrol, NSC 169864) is a sodium channel blocker with IC50 of 131 μM in rat brain synaptosomes.
![eMolecules 1713477-43-0 | 2,7-Dimethyl-1H-purin-6(7H)-one | Ambeed | MFCD26938318 | 164.168 | C7H8N4O | 97.000 | Cc1nc2ncn(C)c2c(=O)[nH]1 | 1g | 572850670](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000223796.jpg-250.jpg)
eMolecules 1713477-43-0 | 2,7-Dimethyl-1H-purin-6(7H)-one | Ambeed | MFCD26938318 | 164.168 | C7H8N4O | 97.000 | Cc1nc2ncn(C)c2c(=O)[nH]1 | 1g | 572850670
2,7-Dimethyl-1H-purin-6(7H)-one | Ambeed | 1713477-43-0 | MFCD26938318 | 164.168 | C7H8N4O | 97.000 | Cc1nc2ncn(C)c2c(=O)[nH]1 | 1g | 572850670
Apexbio Technology LLC Eslicarbazepine acetate 236395-14-5 10mM (in 1mL DMSO)
Eslicarbazepine acetate (CAS 236395-14-5) is an orally administered anticonvulsant prodrug that undergoes rapid first-pass hydrolysis to yield eslicarbazepine its pharmacologically active metabolite Eslicarbazepine predominantly modulates neuronal excitability by stabilizing the inactivated state of voltage-gated sodium channels thereby reducing sustained repetitive neuronal firing associated with seizure activity While approved for adjunctive treatment in partial-onset seizures eslicarbazepine acetate is frequently utilized in research to investigate the pathophysiology of epileptic disorders and to study sodium channel-mediated neuronal signaling
Medchemexpress LLC Oxcarbazepine (Standard) | 28721-07-5 | 99.9% | C₁₅H₁₂N₂O₂ | 5 MG
Oxcarbazepine (Standard) is the analytical standard of Oxcarbazepine, intended for research and analytical applications. It acts as a sodium channel blocker and significantly inhibits glioblastoma cell growth, inducing apoptosis or G2/M arrest in glioblastoma cell lines. It exhibits anti-cancer and anticonvulsant effects.
- Analytical standard grade
- Acts as a sodium channel blocker
- Significantly inhibits glioblastoma cell growth
- Induces apoptosis or G2/M arrest in glioblastoma cell lines
- Exhibits anti-cancer effects
- Exhibits anticonvulsant effects
- Commonly used as a reference standard for assays in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.