Azepines
Selleck Chemical LLC Carbamazepine S1693-1g
Carbamazepine (Carbatrol NSC 169864) is a sodium channel blocker with IC50 of 131 M in rat brain synaptosomes
Medchemexpress LLC Carbamazepine 10,11-epoxide | 36507-30-9 | 99.1% | 252.27 | 25 MG
Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine. This compound exhibits an anticonvulsant effect and is suitable for research related to seizures.
- Orally active metabolite
- Anticonvulsant effect
- Suitable for research of seizures
Selleck Chemical LLC Eslicarbazepine Acetate S4657-100mg
Eslicarbazepine Acetate (BIA 2093 Zebinix Exalief Stedesa Aptiom) an antiepileptic drug is a dual a dual Inhibitor of -Secretase and voltage-gated sodium channel
![eMolecules 28721-07-5 | 9-Oxo-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene-2-carboxamide | Combi-Blocks | MFCD00865307 | 252.273 | C15H12N2O2 | 97.000 | NC(=O)N1c2ccccc2CC(=O)c2ccccc12 | 1g | 205387227](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00128114-205387227.PNG-250.jpg)
eMolecules 28721-07-5 | 9-Oxo-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene-2-carboxamide | Combi-Blocks | MFCD00865307 | 252.273 | C15H12N2O2 | 97.000 | NC(=O)N1c2ccccc2CC(=O)c2ccccc12 | 1g | 205387227
9-Oxo-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene-2-carboxamide | Combi-Blocks | 28721-07-5 | MFCD00865307 | 252.273 | C15H12N2O2 | 97.000 | NC(=O)N1c2ccccc2CC(=O)c2ccccc12 | 1g | 205387227
Apexbio Technology LLC Oxcarbazepine 28721-07-5 50mg
Oxcarbazepine (CAS 28721-07-5) is a small molecule that modulates voltage-gated sodium channels a critical target in neuronal excitability studies It impedes the association of [3H]batrachotoxin ([3H]BTX) with sodium channels demonstrating an IC50 of 160 M and restricts sodium ion influx as indicated by inhibition of 22Na uptake into rat brain synaptosomes with an IC50 of approximately 100 M These properties make oxcarbazepine valuable for investigating sodium channel function and regulation in neuropharmacology and for exploring mechanisms underlying neuronal signaling and excitotoxicity
![eMolecules 1713477-43-0 | 2,7-Dimethyl-1H-purin-6(7H)-one | Ambeed | MFCD26938318 | 164.168 | C7H8N4O | 97.000 | Cc1nc2ncn(C)c2c(=O)[nH]1 | 5g | 847282773](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000483665.jpg-250.jpg)
eMolecules 1713477-43-0 | 2,7-Dimethyl-1H-purin-6(7H)-one | Ambeed | MFCD26938318 | 164.168 | C7H8N4O | 97.000 | Cc1nc2ncn(C)c2c(=O)[nH]1 | 5g | 847282773
2,7-Dimethyl-1H-purin-6(7H)-one | Ambeed | 1713477-43-0 | MFCD26938318 | 164.168 | C7H8N4O | 97.000 | Cc1nc2ncn(C)c2c(=O)[nH]1 | 5g | 847282773
Medchemexpress LLC Conduritol B epoxide | 6090-95-5 | MFCD00077326 | 99.9% | 162.14 g/mol | C6H10O5 | 1 ML
Conduritol B epoxide is an irreversible covalent inhibitor of acid β-glucosidase (GCase) used to block GCase activity in biochemical and cellular studies. It is supplied in solid form and as a 10 mM solution in DMSO for convenient preparation and dosing in research assays.
- Irreversible covalent inhibitor of acid β-glucosidase (GCase).
- Useful for biochemical and cellular assays investigating lysosomal function.
- Available as solid and as a 10 mM solution in DMSO for convenience.
- High reported purity and defined molecular weight for reproducible results.
- Stable under recommended storage conditions to preserve activity.
Cayman Chemical CarbamazepIn 5g
A sodium channel inhibitor; preferentially inhibits inactivated Nav1.7 and Nav1.3 channels (IC50s = 406 and 900 µM, respectively) over resting (closed) Nav1.7 and Nav1.3 channels in whole-cell patch-clamp assays using HEK293 cells (IC50s = 1,584 and 2,464 µM, respectively); inhibits sodium currents in a rat sciatic nerve patch-clamp assay ex vivo at 100 µM; reduces dopamine levels in the striatum and hippocampus, as well as L-DOPA levels in the striatum, in rats at 100 mg/kg; reduces amphetamine-induced hyperactivity in mice at 0.5% w/w in the diet; reduces immobility time in the forced swim test in mice at 0.75% w/w in the diet
![eMolecules 84030-20-6 | 7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene | AA Blocks LLC | MFCD00043004 | 153.229 | C8H15N3 | 0.000 | CN1CCCN2CCCN=C12 | 25g | 784379262](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000482190.jpg-250.jpg)
eMolecules 84030-20-6 | 7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene | AA Blocks LLC | MFCD00043004 | 153.229 | C8H15N3 | 0.000 | CN1CCCN2CCCN=C12 | 25g | 784379262
7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene | AA Blocks LLC | 84030-20-6 | MFCD00043004 | 153.229 | C8H15N3 | 0.000 | CN1CCCN2CCCN=C12 | 25g | 784379262
Medchemexpress LLC Carbamazepine 10,11-epoxide | 36507-30-9 | 99.1% | 252.27 | 5 MG
Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine. Carbamazepine has an anticonvulsant effect and can be used for the research of seizures. This product is for research use only.
- Orally active metabolite
- Anticonvulsant effect, relevant for seizure research
- Appearance: Solid, off-white to light yellow color
- Initial source: Endogenous metabolite
TARGETMOL CHEMICALS INC Carbamazepine 10 11-epoxide 2
Also available in 5 mg, 10 mg, 50 mg, 100 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine. It is formed by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C8 in microsomes from HepG2 cells expressing CYP3A4 or CYP2C8, respectively. Carbamazepine 10,11-epoxide exhibits anticonvulsant activity against maximal electroshock-induced seizures in mice and has been detected in wastewater effluent [1][2][3]. Purity 98.64%