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Azetidine-2-carboxylic acid is a non-proteinogenic amino acid homologue of proline. It is naturally found in common beets and can be misincorporated into proteins across various species, including humans. This compound is also recognized for its toxic and teratogenic properties, making it a valuable tool for specific research applications.
Non-proteinogenic amino acid
Homologue of proline
Found in common beets
Can be misincorporated into proteins
Toxic and teratogenic agent for research purposes
Minimum purity of 98.0%
Appears as a white to off-white solid
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1-Boc-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) 1-Boc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2] /sup
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