Azetidines
eMolecules 345954-83-8 | azetidine-3-carbonitrile hydrochloride | Pharmablock | MFCD09749828 | 118.560 | C4H7ClN2 | 97.000 | Cl.N#CC1CNC1 | 10g | 551056708
azetidine-3-carbonitrile hydrochloride | Pharmablock | 345954-83-8 | MFCD09749828 | 118.560 | C4H7ClN2 | 97.000 | Cl.N#CC1CNC1 | 10g | 551056708
eMolecules 63843-78-7 | 3-(4-Fluoro-phenoxy)-azetidine hydrochloride | J & W PharmLab, LLC | MFCD05664839 | 203.640 | C9H11ClFNO | 96.000 | Cl.Fc1ccc(OC2CNC2)cc1 | 5g | 249977612
3-(4-Fluoro-phenoxy)-azetidine hydrochloride | J & W PharmLab, LLC | 63843-78-7 | MFCD05664839 | 203.640 | C9H11ClFNO | 96.000 | Cl.Fc1ccc(OC2CNC2)cc1 | 5g | 249977612
Medchemexpress LLC Methyl 1-Boc-azetidi | 10g
Methyl 1-Boc-azetidine-3-carboxylate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) Methyl 1-Boc-azetidine-3-carboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1
Medchemexpress LLC Methyl azetidine-3-carboxylate hydrochloride | 100202-39-9 | MFCD01861758 | 99.7% | 151.59 | C5H10ClNO2 | 1 G
Methyl azetidine-3-carboxylate hydrochloride is a methyl-substituted azetidine carboxylate hydrochloride salt supplied as a white to off-white solid for research use. It is used as a non-cleavable ADC linker and as an alkyl chain-based PROTAC linker in medicinal chemistry and conjugation applications.
- High purity (99.7%) suitable for synthesis and conjugation.
- Solid form, white to off-white, easy to handle and weigh.
- Storage: sealed at 4°C; in solvent, -80°C up to 6 months or -20°C up to 1 month.
- Supplied in small research pack sizes (example: 1 G).
- Chemical identifiers: CAS 100202-39-9; formula C5H10ClNO2; molecular weight 151.59.
Medchemexpress LLC NSC319726 (ZMC1) | 71555-25-4 | 99.6% | 234.32 | 100 MG
NSC319726 (ZMC1) is a mutant p53R175 reactivator. It inhibits the growth of fibroblasts expressing the p53R175 mutation with an IC50 of 8 nM, showing no inhibition for p53 wild-type cells. This compound has demonstrated significant inhibition of tumor growth in TOV112D (p53R175H) xenografts in vivo, providing evidence for allele-specific p53 mutant reactivation.
- Mutant p53R175 reactivator with IC50 of 8 nM against p53R175 mutation
- No inhibition for p53 wild-type cells
- High sensitivity for MEF-p53R172H/R172H cell line
- Inhibits tumor growth in TOV112D (p53R175H) xenografts in vivo
- Provides in vivo evidence for allele-specific p53 mutant reactivation
- CC50 < 0.02 μM for Caco-2 cell toxicity
- IC50 < 0.02 μM for Caco-2 cell SARS-CoV-2 cytotoxicity inhibition
- EC50 0.005 μM for TOV112D cell growth inhibition
eMolecules 345954-83-8 | Azetidine-3-carbonitrile Hydrochloride | Accela ChemBio (ASD) | MFCD09749828 | 118.560 | C4H7ClN2 | 97.000 | Cl.N#CC1CNC1 | 1g | 600821954
Azetidine-3-carbonitrile Hydrochloride | Accela ChemBio (ASD) | 345954-83-8 | MFCD09749828 | 118.560 | C4H7ClN2 | 97.000 | Cl.N#CC1CNC1 | 1g | 600821954
eMolecules 1443624-48-3 | 1-(Piperidin-4-yl)azetidin-3-ol hydrochloride | 250mg
Ambeed | 3-(4-Methoxyphenyl)acrylaldehyde | 1g | 595927105 | A132061 | 1963-36-6 | MFCD00017343 | 162.188 | C10H10O2
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Medchemexpress LLC Azetidine-2-carboxylic acid | 2517-04-6 | 98.0% | C4H7NO2 | 25 G
Azetidine-2-carboxylic acid is a non-proteinogenic amino acid homologue of proline, found in common beets. It can be misincorporated into proteins in place of proline in many species, including humans, and is considered a toxic and teratogenic agent. This compound is intended for research use only.
- Non-proteinogenic amino acid homologue of proline
- Found in common beets
- White to off-white solid appearance
- For research use only
- Store solid at 4°C, sealed, away from moisture
- Store in solvent at -80°C for 6 months or -20°C for 1 month
- Soluble in water (50 mg/mL)