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Medchemexpress LLC DB04760 (compound 4) | 544678-85-5 | MFCD09878513 | 99.2% | 410.42 g/mol | C22H20F2N4O2 | 10MG
DB04760 is a small-molecule MMP-13 inhibitor (compound 4) reported as a potent, highly selective, non-zinc-chelating inhibitor with an IC50 of 8 nM. It has been used in studies showing reduction of paclitaxel-induced neurotoxicity and anticancer activity, and is supplied for research use with defined purity and solubility characteristics.
- Potent MMP-13 inhibitor with IC50 = 8 nM.
- Highly selective non-zinc-chelating mechanism.
- Molecular formula C22H20F2N4O2, molecular weight 410.42 g/mol.
- CAS number 544678-85-5.
- Purity 99.2%.
- Soluble in DMSO at ≥100 mg/mL; in vivo formulation: 10% DMSO then 90% corn oil.
- Reported to reduce paclitaxel neurotoxicity and exhibit anticancer activity.
- Available in multiple small-scale pack sizes for research use.
