Benzodiazepines
Clozapine
CAS: 5786-21-0 Molecular Formula: C18H19ClN4 Molecular Weight (g/mol): 326.83 InChI Key: ZUXABONWMNSFBN-UHFFFAOYSA-N IUPAC Name: 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0³,⁸]pentadeca-1,3,5,7,10,12,14-heptaene SMILES: CN1CCN(CC1)C1=C2C=CC=CC2=NC2=CC=C(Cl)C=C2N1
2,3,4,5-Tetrahydro-1H-1,4-benzodiazepine, 95%
CAS: 5946-39-4 Molecular Formula: C9H12N2 Molecular Weight (g/mol): 148.209 MDL Number: MFCD03789577 InChI Key: MLXBHOCKBUILHN-UHFFFAOYSA-N Synonym: 2,3,4,5-tetrahydro-1h-benzo e 1,4 diazepine,1h-1,4-benzodiazepine, 2,3,4,5-tetrahydro,2,3,4,5-tetrahydro-1h benzo e 1,4 diazepine,pubchem14772,acmc-1anok,d0v0nj,tetrahydrobenzo 1,4 diazepine,2,3,4,5-tetrahydro-1h-1,4-benzodiazepine,2,3,4,5-tetrahydro-1h-benzo 1,4 diazepine PubChem CID: 2771762 IUPAC Name: 2,3,4,5-tetrahydro-1H-1,4-benzodiazepine SMILES: C1CNC2=CC=CC=C2CN1
Pirenzepine dihydrochloride, 99%
CAS: 29868-97-1 Molecular Formula: C19H23Cl2N5O2 Molecular Weight (g/mol): 424.326 MDL Number: MFCD00055214 InChI Key: FFNMBRCFFADNAO-UHFFFAOYSA-N Synonym: pirenzepine dihydrochloride,pirenzepine hydrochloride,tabe,bisvanil,leblon,maghen,pirenzepine hcl,pirenzepine 2hcl,ls 519 dihydrochloride,unii-10ym403fls PubChem CID: 71405 ChEBI: CHEBI:32014 IUPAC Name: 11-[2-(4-methylpiperazin-1-yl)acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one;dihydrochloride SMILES: CN1CCN(CC1)CC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4.Cl.Cl
Clozapine 98.0+%, TCI America™
CAS: 5786-21-0 Molecular Formula: C18H19ClN4 Molecular Weight (g/mol): 326.828 MDL Number: MFCD00153785 InChI Key: ZUXABONWMNSFBN-UHFFFAOYSA-N Synonym: clozapine,leponex,clozapin,clozaril,fazaclo,clorazil,iprox,clozapinum,asaleptin,clozapina PubChem CID: 2818 IUPAC Name: 3-chloro-6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepine SMILES: CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl
Medchemexpress LLC Coelenterazine | 55779-48-1 | 98.59% | 423.46 | 1 MG
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. It is used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. Coelenterazine is also a superoxide anion-sensitive chemiluminescent probe and can be used in chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm).
- Luminescent enzyme substrate for apoaequorin and Renilla luciferase.
- Used as a bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions.
- Superoxide anion-sensitive chemiluminescent probe.
- Can be used in chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm).
- Measurement of free radical production.
Medchemexpress LLC Coelenterazine | 55779-48-1 | 98.5% | 423.46 | 1 G
Coelenterazine serves as a luminescent enzyme substrate for both apoaequorin and Renilla luciferase. It has been utilized as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) for detecting protein-protein interactions. Additionally, coelenterazine is a superoxide anion-sensitive chemiluminescent probe and can be employed in the chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm).
- Luminescent enzyme substrate for apoaequorin and Renilla luciferase.
- Used as a bioluminescence donor in BRET to detect protein-protein interactions.
- Superoxide anion-sensitive chemiluminescent probe.
- Can be used in chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm).
Apexbio Technology LLC Coelenterazine 55779-48-1 5mg
Coelenterazine (CAS 55779-48-1) is a small molecule substrate for bioluminescent enzymes that generates a chemiluminescent signal upon oxidation by reactive oxygen species (ROS) particularly superoxide anions and peroxynitrite In rat hepatocytes it exhibits an IC50 of approximately 69 M toward superoxide anions Coelenterazine demonstrates concentration-dependent antioxidant activity enhancing cell viability and decreasing lipid peroxidation under oxidative stress induced by tert-butyl hydroperoxide It is widely applied in biomedical research including ELISA bioluminescence resonance energy transfer (BRET) high-throughput screening (HTS) and in vivo imaging studies of ROS in cancer models
Alkali Scientific Coelenterazine, Native, 1 Milligram
Coelenterazine (1 mg) is a luminescent substrate, laboratory grade, commonly used in bioluminescence assays. This substrate is employed in molecular biology research for the detection and quantification of luciferase activity. Coelenterazine is a substrate for the luciferase enzyme, resulting in light emission when it is metabolized. This reagent is widely used in assays to study gene expression, protein interaction, and various biochemical reactions in cells. It is particularly useful in luminescent reporter assays for tracking cellular processes, drug screening, and biotechnological applications that require precise measurements of biological activity.
Alkali Scientific Coelenterazine H, 1 Mg
Coelenterazine H is a luminescent substrate widely used in biochemical assays, especially in studying the activity of luciferases. This 1mg reagent is used to trigger light emission in the presence of luciferase enzymes, making it valuable for applications in molecular biology, cell biology, and immunology. The light output provides a sensitive and quantifiable measure of enzymatic activity, making Coelenterazine H an essential tool for assay systems such as reporter gene assays and ATP measurements. Its ability to generate light makes it ideal for in vitro and in vivo imaging of biological processes, and it is commonly used in research related to cellular signaling, gene expression, and enzyme kinetics.
Medchemexpress LLC Coelenterazine | 55779-48-1 | 98.59% | 423.46 | 50 MG
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. It has been utilized as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) for detecting protein-protein interactions. Additionally, it serves as a superoxide anion-sensitive chemiluminescent probe for the chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm).
- Luminescent enzyme substrate for apoaequorin and Renilla luciferase
- Used as a bioluminescence donor in BRET to detect protein-protein interactions
- Superoxide anion-sensitive chemiluminescent probe
- Can be used in chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm)
Medchemexpress LLC Coelenterazine | 55779-48-1 | 98.5% | 423.46 | 250 MG
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. It has been used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. Additionally, Coelenterazine functions as a superoxide anion-sensitive chemiluminescent probe and is applicable in the chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm).
- Luminescent enzyme substrate for apoaequorin and Renilla luciferase
- Bioluminescence donor in BRET for protein-protein interaction detection
- Superoxide anion-sensitive chemiluminescent probe
- Used in chemiluminescent detection of peroxynitrite
- Applicable for measurement of free radical production
- Utilized in in vitro and in vivo studies
Medchemexpress LLC FAUC 365 25mg | 474432-66-1 | 25 MG
FAUC 365 is a selective dopamine D3 receptor antagonist used as a research reagent to probe D3-mediated signaling in neuropharmacology and CNS disease models.
- Highly selective dopamine D3 receptor antagonist (Ki = 0.5 nM).
- Lower potency at related receptors (D4.4 Ki ≈ 340 nM; D2short Ki ≈ 2,600 nM; D2Long Ki ≈ 3,600 nM).
- Chemical formula C23H25Cl2N3OS; molecular weight 462.44 g/mol.
- Purity ~98.8% as supplied.
- Appearance: off-white to light yellow solid.
- Storage: powder -20°C for long-term storage; 4°C for shorter term.
- Supplied as 25 mg research quantity.
Medchemexpress LLC Coelenterazine | 55779-48-1 | 98.5% | 423.46 | 25 MG
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. It has been utilized as a bioluminescence donor in bioluminescence resonance energy transfer (BRET) for detecting protein-protein interactions. It also serves as a superoxide anion-sensitive chemiluminescent probe and can be employed in the chemiluminescent detection of peroxynitrite.
- Functions as a luminescent enzyme substrate
- Used as a bioluminescence donor in BRET for protein-protein interaction detection
- Acts as a superoxide anion-sensitive chemiluminescent probe
- Can be used for chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm)
Medchemexpress LLC Coelenterazine | 55779-48-1 | 98.45% | 423.46 | 100 MG
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. It has been used as a bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. It is also a superoxide anion-sensitive chemiluminescent probe that can be used in the chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm).
- Luminescent enzyme substrate for apoaequorin and Renilla luciferase.
- Used in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions.
- Superoxide anion-sensitive chemiluminescent probe.
- Can be used in chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm).
- For research use only.
Medchemexpress LLC Coelenterazine | 55779-48-1 | 98.59% | 423.46 | 500 MG
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. It has been used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. This compound is also a superoxide anion-sensitive chemiluminescent probe and can be used in chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm).
- Luminescent enzyme substrate for apoaequorin and Renilla luciferase.
- Used as a bioluminescence donor in BRET to detect protein-protein interactions.
- Superoxide anion-sensitive chemiluminescent probe.
- Can be used in chemiluminescent detection of peroxynitrite.