Benzodioxanes

Aromatic organic heterocyclic compounds that consist of benzene fused with a dioxane ring; dioxane rings are six-membered heterocyclic compounds with two oxygen atoms, and are considered ethers.

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Aobchem AOBCHEM

5001003954 1-BROMO-4- 2-BROMOETHOXY -2-FL

Pricing & Availability

Medchemexpress LLC BI-3663 | 2341740-84-7 | 99.8% | 917.84 | 100 MG

BI-3663 is a highly selective PTK2/FAK PROTAC (DC50=30 nM) that utilizes Cereblon ligands to hijack E3 ligases for PTK2 degradation. It inhibits PTK2 with an IC50 of 18 nM. BI-3663 is composed of BI-4464 (HY-124625) linked to Pomalidomide (HY-10984) with a linker, and demonstrates anti-cancer activity.

Highly selective PTK2/FAK PROTAC
Inhibits PTK2 with an IC50 of 18 nM
Utilizes Cereblon ligands for PTK2 degradation
Composed of BI-4464 linked to Pomalidomide with a linker
Exhibits anti-cancer activity
Potently degrades PTK2 in Hep3B2.1-7 cells and A549 cells

Pricing & Availability

eMolecules 86864-60-0 | 2-Bromoethoxy-t-butyl dimethylsilane | Key Organics/BIONET | MFCD00209550 | 239.228 | C8H19BrOSi | 97.000 | CC(C)(C)[Si](C)(C)OCCBr | 10mg | 564133838

2-Bromoethoxy-t-butyl dimethylsilane | Key Organics/BIONET | 86864-60-0 | MFCD00209550 | 239.228 | C8H19BrOSi | 97.000 | CC(C)(C)[Si](C)(C)OCCBr | 10mg | 564133838